TL;DR: UnitedHealthcare modified its pain management rehabilitation coverage policy (pain-management-rehabilitation) for Medicare Advantage members, effective November 2, 2025. Here's what billing teams need to do.
UnitedHealthcare updated its Medicare Advantage pain management coverage policy across a wide range of interventional procedures—including SI joint denervation (CPT 64625), genicular nerve blocks (CPT 64454), radiofrequency ablation of the basivertebral nerve (CPT 64628, 64629), percutaneous cryoneurolysis (CPT 0440T, 0441T, 0442T), and occipital nerve procedures (CPT 64405, 64722, 64744). The core change: coverage for most of these procedures now routes through local coverage determinations (LCDs) and local coverage articles (LCAs) from Medicare Administrative Contractors, and compliance with those regional policies is required where they exist. If your practice bills any of these pain codes for Medicare Advantage members, your LCD compliance becomes the first line of defense against claim denial.
Quick-Reference Table
| Field | Detail |
|---|---|
| Payer | UnitedHealthcare (Medicare Advantage) |
| Policy | Pain Management – Medicare Advantage Medical Policy |
| Policy Code | pain-management-rehabilitation |
| Change Type | Modified |
| Effective Date | November 2, 2025 |
| Impact Level | High |
| Specialties Affected | Pain management, interventional spine, orthopedics, neurology, physical medicine & rehabilitation |
| Key Action | Verify your MAC's LCD/LCA requirements for each procedure code before billing UHC Medicare Advantage claims after November 2, 2025 |
UnitedHealthcare Pain Management Coverage Criteria and Medical Necessity Requirements 2025
The pain-management-rehabilitation UHC policy covers a broad set of interventional pain procedures—but coverage is not uniform. For most of the higher-complexity procedures, there is no National Coverage Determination (NCD) from CMS. That means UnitedHealthcare defers to your Medicare Administrative Contractor's LCDs and LCAs.
This is the critical point: if an LCD or LCA exists in your region, compliance is required. UHC will not apply a blanket national standard where a regional one exists. If your MAC has documented medical necessity criteria for SI joint denervation under CPT 64625, those criteria govern your UHC Medicare Advantage claims too.
For procedures where no LCD or LCA exists at all—like cooled radiofrequency ablation (CRFA) of the genicular nerve (CPT 64999) or decompression and transection of the greater occipital nerve (CPT 64722, 64744)—UHC routes coverage decisions to its own Commercial Medical Policy documents. Specifically: the Commercial policy titled "Occipital Nerve Injections and Ablation" governs occipital nerve decompression/transection, and "Omnibus Codes" governs CRFA of the genicular nerve and percutaneous cryoneurolysis where no LCD exists.
Electrical stimulators for pain management—including percutaneous electrical nerve stimulation (PENS) and percutaneous neuromodulation therapy (PNT)—are covered when medical necessity criteria are met. UHC directs you to the separate Medicare Advantage Medical Policy titled "Electrical Stimulators" for those criteria. If your team bills these under the pain management policy, recheck your coding pathways.
Massage therapy is not covered as a standalone service. The single exception: massage is covered if it is part of a multi-modality treatment plan appropriate to the member's diagnosis and administered with a licensed therapist in attendance. If you're billing massage as part of a pain management program, document the authorized multi-modality plan and confirm a licensed therapist is present and recorded in the clinical record for every claim.
The real issue with this policy is the LCD-first structure. Your reimbursement exposure depends heavily on which MAC jurisdiction your practice sits in. Two practices billing CPT 64625 for SI joint denervation could face completely different coverage criteria depending on their region. Check your MAC's LCD before billing.
UnitedHealthcare Pain Management Exclusions and Non-Covered Indications
Standalone massage therapy is not covered. Full stop. The multi-modality exception is narrow—it requires an appropriate multi-modality treatment plan, an appropriate diagnosis, and a licensed therapist in attendance. Missing any one of those elements makes the claim non-covered.
Pulsed radiofrequency ablation (pulsed RFA) for spinal pain has no NCD. The source policy data for pulsed RFA is truncated, so LCD/LCA applicability cannot be confirmed from the available information. Consult the full UHC pain-management-rehabilitation policy directly to determine which LCDs apply in your region and what commercial policy governs where no LCD exists.
The Intracept procedure—RFA of the intraosseous basivertebral nerve, billed under CPT 22899 (unlisted) or CPT 64628/64629—is also LCD-dependent. LCDs do exist for this procedure in some regions. If you're in a region without one, UHC defaults to its Commercial "Ablative Treatment for Spinal Pain" policy. Confirm which standard applies in your jurisdiction before billing.
Coverage Indications at a Glance
| Indication | Status | Relevant Codes | Notes |
|---|---|---|---|
| Electrical stimulators (PENS, PNT) for pain | Covered when criteria met | Per "Electrical Stimulators" policy | Refer to separate UHC Medicare Advantage policy for criteria |
| Massage therapy | Not covered (standalone) | N/A | Covered only as part of authorized multi-modality plan appropriate to diagnosis, with licensed therapist in attendance |
| SI joint denervation | LCD/LCA-dependent | CPT 64625 | No NCD; must comply with MAC LCD where applicable; commercial policy applies where no LCD exists |
| Greater occipital nerve injection | LCD/LCA-dependent | CPT 64405 | No NCD; MAC LCD governs where applicable |
| Decompression/transection of greater occipital nerve | Commercial policy (no LCD) | CPT 64722, 64744 | No NCD, no LCDs; refer to UHC Commercial "Occipital Nerve Injections and Ablation" policy |
| RFA of intraosseous basivertebral nerve (Intracept) | LCD/LCA-dependent | CPT 22899, 64628, 64629 | No NCD; LCDs exist in some regions; commercial policy applies where no LCD exists |
| Genicular nerve block (GNB) and RFA for chronic knee pain | LCD/LCA-dependent | CPT 64454, 64624 | No NCD; MAC LCD governs where applicable |
| Cooled RFA (CRFA) of genicular nerve | Commercial policy (no LCD) | CPT 64999 | No NCD, no LCDs; refer to UHC Commercial "Omnibus Codes" policy |
| Percutaneous cryoneurolysis (e.g., iovera° system) | LCD/LCA-dependent | CPT 0440T, 0441T, 0442T | No NCD; LCDs exist in some regions; commercial policy applies where no LCD exists |
| Pulsed RFA for spinal pain | LCD/LCA status unconfirmed from available data | Per applicable policy | No NCD; consult full UHC policy for LCD applicability and commercial policy fallback in your region |
UnitedHealthcare Pain Management Billing Guidelines and Action Items 2025
The effective date of November 2, 2025 has already passed. If your team hasn't audited LCD compliance for these procedures yet, do it now.
| # | Action Item |
|---|---|
| 1 | Pull your MAC's active LCDs for every procedure in this policy. For CPT 64625 (SI joint denervation), CPT 64405 (greater occipital nerve injection), CPT 64454 and 64624 (genicular nerve block and RFA), CPT 22899/64628/64629 (Intracept), and CPT 0440T–0442T (cryoneurolysis), find your MAC's LCD and confirm whether it's still active. CMS's LCD database is your starting point. Update your charge capture to flag any procedure without a confirmed active LCD in your region. |
| 2 | For procedures with no LCD in your region, pull the relevant UHC Commercial policy. Occipital nerve decompression (CPT 64722, 64744) and CRFA of the genicular nerve (CPT 64999) have no LCDs anywhere—UHC routes these to Commercial policies. Get those policies in front of your clinical documentation team now. Medical necessity criteria in the Commercial policies are the standard for your claims. |
| 3 | Audit your massage therapy billing immediately. If any massage therapy claims are going out under a pain management plan for UHC Medicare Advantage members, confirm that each claim ties to a multi-modality treatment plan appropriate to the member's diagnosis, with a licensed therapist documented in attendance. A claim denial here is easy to avoid with the right documentation. |
| 4 | Check prior authorization requirements by procedure and by MAC jurisdiction. This policy does not specify prior authorization requirements. Requirements vary by MAC LCD and by procedure. Do not assume prior auth requirements are consistent across procedures or jurisdictions. Verify each one individually using your MAC's published LCD. |
| 5 | For CPT 64999 (unlisted — CRFA of genicular nerve) and CPT 22899 (unlisted — Intracept), document your code selection in writing. Unlisted codes require detailed operative notes and a written explanation of why no specific code applies. UHC reviewers will scrutinize these. Attach documentation to the claim and keep it in your records. |
| 6 | If you're billing cryoneurolysis under CPT 0440T, 0441T, or 0442T, confirm your MAC jurisdiction. LCDs for percutaneous cryoneurolysis exist in some regions but not all. The iovera° system specifically is called out in this policy. Reimbursement for these Category III codes varies by payer and region. |
| 7 | Talk to your compliance officer if you're unsure which policy governs a specific procedure in your state. The LCD-or-commercial-policy-as-fallback structure creates real ambiguity for multisite practices. One wrong assumption can produce a pattern of claim denials across multiple dates of service. |
| Previous Version | Current Version |
|---|---|
| Coverage is considered experimental and investigational for all indications | Coverage is considered medically necessary when specific criteria are met |
| Prior authorization is not required | Prior authorization is required for initial treatment |
| Documentation must include clinical history | Documentation must include clinical history |
| Re-review every 24 months | Re-review every 12 months with updated clinical documentation |
CPT, HCPCS, and ICD-10 Codes for Pain Management Under pain-management-rehabilitation
Covered CPT Codes (When Coverage Criteria and LCD Requirements Are Met)
| Code | Type | Description | Coverage Group |
|---|---|---|---|
| 64625 | CPT | Radiofrequency ablation, nerves innervating the sacroiliac joint, with image guidance | SI Joint Denervation |
| 64405 | CPT | Injection(s), anesthetic agent(s) and/or steroid; greater occipital nerve | Greater Occipital Nerve Injection |
| 64722 | CPT | Decompression: unspecified nerve(s) (specify) | Decompression/Transection of Greater Occipital Nerve |
| 64744 | CPT | Transection or avulsion of; greater occipital nerve | Decompression/Transection of Greater Occipital Nerve |
| 64454 | CPT | Injection(s), anesthetic agent(s) and/or steroid; genicular nerve branches, including imaging guidance | GNB and RFA for Chronic Knee Pain |
| 64624 | CPT | Destruction by neurolytic agent, genicular nerve branches including imaging guidance, when performed | GNB and RFA for Chronic Knee Pain |
| 64628 | CPT | Thermal destruction of intraosseous basivertebral nerve, including all imaging guidance; first 2 vertebral levels | RFA of Intraosseous BVN (Intracept) |
| 64629 | CPT | Thermal destruction of intraosseous basivertebral nerve, including all imaging guidance; each additional vertebral level | RFA of Intraosseous BVN (Intracept) |
| 0440T | CPT | Ablation, percutaneous, cryoablation, includes imaging guidance; upper extremity distal/peripheral nerve | Percutaneous Cryoneurolysis |
| 0441T | CPT | Ablation, percutaneous, cryoablation, includes imaging guidance; lower extremity distal/peripheral nerve | Percutaneous Cryoneurolysis |
| 0442T | CPT | Ablation, percutaneous, cryoablation, includes imaging guidance; nerve plexus or other truncal nerve | Percutaneous Cryoneurolysis |
Unlisted Codes Requiring Special Documentation
| Code | Type | Description | Notes |
|---|---|---|---|
| 64999 | CPT | Unlisted procedure, nervous system | Used to report CRFA of genicular nerve; requires detailed documentation |
| 22899 | CPT | Unlisted procedure, spine | Used to report the Intracept procedure; requires detailed documentation |
Note: No ICD-10-CM codes are listed in this policy document. Medical necessity diagnosis requirements are defined within the applicable LCD/LCA or UHC Commercial policy for each procedure.
Get the Full Picture for CPT 64625
Track this policy across versions, search 1,500+ policies by CPT code, and get real-time alerts when any payer changes coverage.