Aetna modified CPB 0739 for functional magnetic resonance imaging (fMRI), effective November 27, 2025. Here's what changes for billing teams.
Aetna, a CVS Health company, updated its fMRI coverage policy under CPB 0739 in the Aetna system. The policy governs CPT codes 70554 and 70555 — the two codes your team bills for functional MRI of the brain. The update draws a hard line between covered pre-surgical use and a long list of conditions the payer treats as experimental. If your facility bills fMRI for anything outside that narrow pre-surgical window, expect denials.
Quick-Reference Table
| Field | Detail |
|---|---|
| Payer | Aetna |
| Policy | Functional Magnetic Resonance Imaging |
| Policy Code | CPB 0739 |
| Change Type | Modified |
| Effective Date | November 27, 2025 |
| Impact Level | High |
| Specialties Affected | Neurosurgery, Neurology, Radiology, Epilepsy Surgery Programs |
| Key Action | Audit all fMRI claims billed under CPT 70554 and 70555 against the covered indication list before submitting for dates of service on or after November 27, 2025 |
Aetna fMRI Coverage Criteria and Medical Necessity Requirements 2025
Aetna's fMRI coverage policy under CPB 0739 is narrow by design. The payer considers CPT 70554 and 70555 medically necessary for exactly one purpose: identifying the eloquent cortex during pre-surgical evaluation.
Three conditions qualify for covered use:
| # | Covered Indication |
|---|---|
| 1 | Brain tumors — except temporal tumors |
| 2 | Epilepsy — except temporal neocortical epilepsy |
| 3 | Vascular malformations |
That's it. Medical necessity under this policy requires a documented pre-surgical context and one of those three diagnoses. The relevant ICD-10-CM codes run from C71.0–C71.9 for malignant brain neoplasms, C79.31–C79.49 for secondary malignant neoplasms, D33.0–D33.2 for benign brain neoplasms, and D43.0–D43.4 for neoplasms of uncertain behavior. Those are the codes that will support a covered claim.
If a physician orders fMRI for pre-surgical planning and the diagnosis falls outside those ICD-10 categories, the claim will not meet medical necessity criteria. Document the surgical indication clearly in the medical record before you submit.
This policy does not specify prior authorization requirements in the CPB text itself. That does not mean prior auth is off the table — Aetna plan-level rules vary, and many commercial and managed care plans add prior authorization requirements on top of CPB criteria. Check the member's specific plan benefits before billing CPT 70554 or 70555. If your team isn't doing that routinely, start now.
Aetna fMRI Exclusions and Non-Covered Indications
This is where the policy gets expensive for billing teams who aren't paying attention.
Aetna labels fMRI experimental, investigational, or unproven for a wide range of neurological and psychiatric conditions. The payer's position is that clinical evidence does not support fMRI for diagnosis, monitoring, prognosis, or surgical management of these conditions. That language — "diagnosis, monitoring, prognosis, or surgical management" — covers virtually every clinical use case outside the pre-surgical eloquent cortex mapping described above.
The excluded indications include conditions many neurologists and psychiatrists use fMRI to study routinely. That clinical use and billable coverage are two different things is the real issue here. Researchers and academic centers run fMRI for many of these conditions. Aetna does not pay for it.
Here's the full exclusion list from CPB 0739:
| # | Excluded Procedure |
|---|---|
| 1 | Alzheimer's disease |
| 2 | Anger and aggressive behaviors |
| 3 | Anxiety disorder |
| 4 | Anoxic-ischemic brain injury |
| 5 | Attention-deficit hyperactivity disorder (ADHD) |
| 6 | Autism spectrum disorder |
| 7 | Bipolar disorder |
| 8 | Childhood maltreatment |
| 9 | Chronic pain, including fibromyalgia |
| 10 | Disorders of consciousness (locked-in syndrome, minimally conscious state, coma/vegetative state) |
| 11 | Emotion-expressive suppression |
| 12 | Migraines |
| 13 | Multiple sclerosis |
| 14 | Obsessive-compulsive disorder (OCD) |
| 15 | Panic disorder |
| 16 | Parkinson's disease |
| 17 | Psychosis |
| 18 | Psychotic depression |
| 19 | Schizophrenia |
| 20 | Sleep behavior disorder |
| 21 | Stroke and stroke rehabilitation |
| 22 | Trauma, including head injury |
| 23 | Temporal neocortical epilepsy (carved out from the covered epilepsy indication) |
| 24 | Temporal tumors (carved out from the covered brain tumor indication) |
Those last two are the ones that trip up billing teams the most. The policy covers fMRI for epilepsy — but not temporal neocortical epilepsy. It covers fMRI for brain tumors — but not temporal tumors. If you're at an epilepsy surgery center or a neuro-oncology program, your team must verify tumor or seizure focus location before billing. A temporal lobe tumor under C71.2 can still land a denial under this policy if the surgical site is temporal.
If your practice manages a high volume of psychiatric patients and anyone has ordered fMRI for ADHD (F90.1–F90.9), autism (F84.0–F84.9), bipolar disorder (F30.10–F31.9), schizophrenia (F20.0–F20.9), OCD (F42.2–F42.9), or anxiety (F41.0–F41.9), those claims will not be covered under this policy. Document and bill accordingly — or prepare for claim denial.
Coverage Indications at a Glance
| Indication | Status | Relevant Codes | Notes |
|---|---|---|---|
| Pre-surgical eloquent cortex mapping — brain tumors (non-temporal) | Covered | CPT 70554, 70555; C71.0–C71.9, D33.0–D33.2, D43.0–D43.4, C79.31–C79.49 | Medical necessity documentation required; confirm plan-level prior auth |
| Pre-surgical eloquent cortex mapping — epilepsy (non-temporal neocortical) | Covered | CPT 70554, 70555 | Must confirm seizure focus is not temporal neocortical |
| Pre-surgical eloquent cortex mapping — vascular malformations | Covered | CPT 70554, 70555 | Same documentation requirements |
| Temporal neocortical epilepsy | Experimental | CPT 70554, 70555 | Specifically excluded from the covered epilepsy indication |
| Temporal tumors | Experimental | CPT 70554, 70555 | Specifically excluded from the covered brain tumor indication |
| Alzheimer's disease | Experimental | CPT 70554, 70555 | No covered indication |
| ADHD | Experimental | CPT 70554, 70555; F90.1–F90.9 | No covered indication |
| Autism spectrum disorder | Experimental | CPT 70554, 70555; F84.0–F84.9 | No covered indication |
| Bipolar disorder | Experimental | CPT 70554, 70555; F30.10–F31.9 | No covered indication |
| Anxiety disorder | Experimental | CPT 70554, 70555; F41.0–F41.9 | No covered indication |
| OCD | Experimental | CPT 70554, 70555; F42.2–F42.9 | No covered indication |
| Schizophrenia / Psychosis | Experimental | CPT 70554, 70555; F20.0–F20.9, F25.0–F25.9, F29 | No covered indication |
| Chronic pain / fibromyalgia | Experimental | CPT 70554, 70555 | No covered indication |
| Stroke / stroke rehabilitation | Experimental | CPT 70554, 70555 | No covered indication |
| Multiple sclerosis | Experimental | CPT 70554, 70555 | No covered indication |
| Parkinson's disease | Experimental | CPT 70554, 70555 | No covered indication |
| Migraines | Experimental | CPT 70554, 70555 | No covered indication |
| Trauma / head injury | Experimental | CPT 70554, 70555 | No covered indication |
| Sleep behavior disorder | Experimental | CPT 70554, 70555 | No covered indication |
| Disorders of consciousness | Experimental | CPT 70554, 70555 | Includes locked-in syndrome, vegetative state, minimally conscious state |
| Psychotic depression | Experimental | CPT 70554, 70555; F32.3, F33.3 | No covered indication |
| Panic disorder | Experimental | CPT 70554, 70555 | No covered indication |
| Anoxic-ischemic brain injury | Experimental | CPT 70554, 70555 | No covered indication |
Aetna fMRI Billing Guidelines and Action Items 2025
The effective date is November 27, 2025. Here's what your billing team should do now.
| # | Action Item |
|---|---|
| 1 | Audit your fMRI charge capture for CPT 70554 and 70555. Pull every claim for these codes from the past 90 days and verify the ICD-10 diagnosis matches a covered indication. Any claim sitting in your queue with a psychiatric or non-surgical diagnosis is a denial waiting to happen. |
| 2 | Flag temporal tumor and temporal neocortical epilepsy cases before they hit the claim. These are the high-risk edge cases. Build a hard stop into your charge capture or prior auth workflow so that C71.2 (temporal lobe malignant neoplasm) and similar temporal diagnoses get reviewed before submission under this policy. |
| 3 | Verify plan-level prior authorization requirements for every Aetna member. CPB 0739 sets the medical necessity floor. Individual plan documents may require prior auth on top of that. Reimbursement depends on meeting both the CPB criteria and any plan-level utilization management rules. |
| 4 | Update your denial management protocols for the experimental indication list. If your facility receives a denial for fMRI billed with any of the 22+ excluded conditions, don't waste appeal cycles arguing clinical utility. Aetna's position is documented. Pursue appeals only with strong evidence that the claim meets the narrow covered criteria — or escalate to your compliance officer. |
| 5 | Educate ordering physicians on the covered scope. Neurologists and neuroradiologists sometimes order CPT 70554 or 70555 under broad clinical language. A clear one-page summary of what Aetna covers under CPB 0739 — pre-surgical eloquent cortex mapping for non-temporal brain tumors, non-temporal neocortical epilepsy, and vascular malformations — reduces orders that will never be covered. |
| 6 | Check CPB 0279 if you also bill for magnetoencephalography. Aetna cross-references magnetic source imaging and MEG billing under a separate policy. If your program offers both fMRI and MEG for pre-surgical mapping, review CPB 0279 alongside 0739 to make sure your billing guidelines are aligned across both modalities. |
If you manage fMRI billing for a research-affiliated program or academic medical center, loop in your compliance officer before the November 27 effective date. The line between clinical care and research use of fMRI is real, but payers don't always distinguish between them when a claim hits their system.
| Previous Version | Current Version |
|---|---|
| Coverage is considered experimental and investigational for all indications | Coverage is considered medically necessary when specific criteria are met |
| Prior authorization is not required | Prior authorization is required for initial treatment |
| Documentation must include clinical history | Documentation must include clinical history |
| Re-review every 24 months | Re-review every 12 months with updated clinical documentation |
CPT, HCPCS, and ICD-10 Codes for fMRI Under CPB 0739
Covered CPT Codes (When Selection Criteria Are Met)
| Code | Type | Description |
|---|---|---|
| 70554 | CPT | Magnetic resonance imaging, brain, functional MRI; including test selection and administration of neurofunctional testing |
| 70555 | CPT | Magnetic resonance imaging, brain, functional MRI; requiring physician or psychologist administration of entire neurofunctional testing |
Key ICD-10-CM Diagnosis Codes
Covered Diagnoses (Brain Tumors and Neoplasms)
| Code | Description |
|---|---|
| C71.0 | Malignant neoplasm of brain |
| C71.1 | Malignant neoplasm of brain |
| C71.2 | Malignant neoplasm of brain |
| C71.3 | Malignant neoplasm of brain |
| C71.4 | Malignant neoplasm of brain |
| C71.5 | Malignant neoplasm of brain |
| C71.6 | Malignant neoplasm of brain |
| C71.7 | Malignant neoplasm of brain |
| C71.8 | Malignant neoplasm of brain |
| C71.9 | Malignant neoplasm of brain |
| C79.31 | Secondary malignant neoplasm of brain and other parts of nervous system |
| C79.32 | Secondary malignant neoplasm of brain and other parts of nervous system |
| C79.33–C79.49 | Secondary malignant neoplasm of brain and other parts of nervous system (additional specificity codes) |
| D33.0 | Benign neoplasm of brain |
| D33.1 | Benign neoplasm of brain |
| D33.2 | Benign neoplasm of brain |
| D43.0 | Neoplasm of uncertain behavior of brain and spinal cord |
| D43.1 | Neoplasm of uncertain behavior of brain and spinal cord |
| D43.2 | Neoplasm of uncertain behavior of brain and spinal cord |
| D43.4 | Neoplasm of uncertain behavior of brain and spinal cord |
Note on C71.2: Temporal lobe malignant neoplasm appears in the ICD-10 code set listed under this policy, but temporal tumors are explicitly excluded from covered fMRI indications. Do not bill CPT 70554 or 70555 with C71.2 expecting reimbursement under CPB 0739.
Experimental / Non-Covered Diagnosis Codes (Documented in Policy)
| Code | Description |
|---|---|
| F20.0–F20.9 | Schizophrenia |
| F25.0–F25.9 | Schizoaffective disorders |
| F29 | Unspecified psychosis not due to a substance or known physiological condition |
| F30.10–F31.9 | Bipolar I and II disorders |
| F32.3 | Major depressive disorder, single episode, severe with psychotic features |
| F33.3 | Major depressive disorder, recurrent, severe with psychotic symptoms |
| F41.0–F41.9 | Anxiety disorders |
| F42.2–F42.9 | Obsessive-compulsive disorder |
| F84.0–F84.9 | Pervasive developmental disorders (including autism spectrum disorder) |
| F90.1–F90.9 | Attention-deficit hyperactivity disorder |
Claims pairing CPT 70554 or 70555 with any of these diagnosis codes will not meet Aetna's medical necessity criteria under CPB 0739.
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