Aetna modified CPB 0609 for laser photocoagulation of drusen, effective December 4, 2025. CPT 67220 remains non-covered for all drusen-related indications under Aetna plans.
Aetna, a CVS Health company, updated Clinical Policy Bulletin 0609 — its laser photocoagulation of drusen coverage policy — with this December 4, 2025 revision. The policy classifies laser photocoagulation of macular drusen as experimental, investigational, or unproven. That includes sub-threshold laser techniques. Any claim submitted under CPT 67220 for drusen treatment or age-related macular degeneration (AMD) prevention will be denied.
This matters beyond a single procedure. Ophthalmology practices billing Aetna for AMD-related procedures need to know exactly where the line sits — and this policy draws it clearly.
Quick-Reference: Aetna CPB 0609 Laser Photocoagulation of Drusen
| Field | Detail |
|---|---|
| Payer | Aetna, a CVS Health company |
| Policy Title | Laser Photocoagulation of Drusen |
| Policy Code | CPB 0609 |
| Change Type | Modified |
| Effective Date | December 4, 2025 |
| Impact Level | Medium — direct denial risk for CPT 67220 billed under drusen or AMD diagnoses |
| Specialties Affected | Ophthalmology, Retinal Surgery, Optometry (referral-based) |
| Key Action | Remove CPT 67220 from any charge capture template tied to drusen or AMD diagnosis codes before billing Aetna claims dated December 4, 2025 or later |
Aetna Laser Photocoagulation of Drusen Coverage Criteria and Medical Necessity Requirements 2025
The Aetna laser photocoagulation coverage policy under CPB 0609 is straightforward: there are no covered indications for this procedure when used to treat or prevent AMD via macular drusen reduction.
Aetna does not recognize laser photocoagulation — including sub-threshold laser photocoagulation — as meeting medical necessity criteria for drusen treatment. The policy language is unambiguous. The procedure "has not been shown to be effective and may be associated with loss of visual acuity." That's not soft language. Aetna is citing clinical harm as part of its rationale.
Prior authorization for CPT 67220 is irrelevant here. You can't authorize a procedure that's classified as experimental. Getting a prior auth on a non-covered service doesn't create a payment obligation — and your team shouldn't spend time pursuing one for this indication.
The reimbursement risk is real. If your billing team is submitting CPT 67220 paired with any of the ICD-10 codes in this policy — H35.30 through H35.3293 for AMD, H35.361 through H35.369 for macular drusen, or the choroidal degeneration codes in the H31.10x range — expect denial. Confirm whether this CPB applies to your specific Aetna contract type, including any Medicare Advantage arrangements.
Aetna Laser Photocoagulation of Drusen Exclusions and Non-Covered Indications
This entire policy is an exclusion. Every indication listed in CPB 0609 is non-covered.
Aetna classifies laser photocoagulation of macular drusen — including sub-threshold laser photocoagulation — as experimental, investigational, or unproven. This applies to two distinct use cases: treatment of existing drusen and prevention of AMD progression. Neither is covered.
Aetna's stated rationale is that the procedure "has not been shown to be effective and may be associated with loss of visual acuity." That doesn't make the denial easier to manage, but it does mean this policy isn't going to flip on appeal without extraordinary documentation.
Sub-threshold laser is explicitly called out. If your retina specialist is billing sub-threshold techniques as a distinct approach hoping to sidestep the experimental designation, that won't work under this policy. Aetna groups it in the same non-covered bucket.
Coverage Indications at a Glance
| Indication | Status | Relevant Codes | Notes |
|---|---|---|---|
| Laser photocoagulation of macular drusen | Not Covered / Experimental | CPT 67220; H35.361–H35.369 | Classified as experimental, investigational, or unproven |
| Sub-threshold laser photocoagulation of macular drusen | Not Covered / Experimental | CPT 67220; H35.361–H35.369 | Explicitly included in the experimental designation |
| Laser photocoagulation for AMD prevention | Not Covered / Experimental | CPT 67220; H35.30–H35.3293 | No evidence of effectiveness per Aetna clinical review |
| Laser photocoagulation for AMD treatment | Not Covered / Experimental | CPT 67220; H35.30–H35.3293 | Associated with potential vision loss per Aetna |
| Laser photocoagulation for choroidal degeneration (drusen context) | Not Covered / Experimental | CPT 67220; H31.101–H31.129 | Non-covered when billed with choroidal degeneration codes in drusen context |
| Laser photocoagulation for drusen of optic disc | Not Covered / Experimental | CPT 67220; H47.321–H47.329 | All laterality variants covered by this exclusion |
Aetna Laser Photocoagulation Billing Guidelines and Action Items 2025
| # | Action Item |
|---|---|
| 1 | Audit your CPT 67220 charge capture templates immediately. Pull every template in your ophthalmology or retina practice that includes CPT 67220. Check whether any are paired with ICD-10 codes in the H35.30–H35.3293, H35.361–H35.369, H31.101–H31.129, or H47.321–H47.329 ranges. If they are, flag those encounters for review before submitting to Aetna. |
| 2 | Do not submit CPT 67220 for drusen indications on claims dated December 4, 2025 or later. The effective date of this policy revision is December 4, 2025. Any claim submitted on or after that date for laser photocoagulation under a drusen or AMD diagnosis will be denied under CPB 0609. |
| 3 | Identify any claims already in your billing queue. If you have claims in progress — encounters performed before December 4, 2025 but not yet submitted — verify the applicable policy version. The prior policy version may apply, but check your payer contract terms and confirm with your billing consultant before submitting. |
| 4 | Set up claim denial tracking for CPT 67220 across all Aetna plan types. Your denial management team should flag every CPT 67220 denial from Aetna. Some of those denials may be appropriate under CPB 0609. Others may be for non-drusen indications — which may have separate coverage status. Don't let CPB 0609 denials get mixed in with other CPT 67220 claim denials. Aetna's related policy CPB 0701 on VEGF inhibitors for ocular indications governs some overlapping clinical territory. |
| 5 | Brief your retina and ophthalmology providers on the sub-threshold laser language. Some providers may believe sub-threshold laser is clinically distinct enough to warrant a separate coverage argument. Under this policy, it isn't. If your practice is using sub-threshold laser photocoagulation for drusen, document that you've informed providers of the Aetna non-covered designation. This protects your practice if a patient expects Aetna reimbursement. |
| 6 | Confirm which Aetna contract types this CPB applies to. Confirm whether CPB 0609 applies to your specific Aetna contract type, including any Medicare Advantage arrangements. Don't assume this CPB's scope matches your full Aetna payer mix without verifying. |
| 7 | If patient demand for this procedure exists, use an ABN-equivalent process. For Aetna members, use a financial responsibility waiver before performing laser photocoagulation for drusen. The procedure isn't medically necessary under Aetna's definition. If your patient wants to proceed, they need to understand they're paying out of pocket. Document that conversation. |
| Previous Version | Current Version |
|---|---|
| Coverage is considered experimental and investigational for all indications | Coverage is considered medically necessary when specific criteria are met |
| Prior authorization is not required | Prior authorization is required for initial treatment |
| Documentation must include clinical history | Documentation must include clinical history |
| Re-review every 24 months | Re-review every 12 months with updated clinical documentation |
CPT, HCPCS, and ICD-10 Codes for Laser Photocoagulation of Drusen Under CPB 0609
Not Covered / Experimental CPT Codes
| Code | Type | Description | Reason |
|---|---|---|---|
| 67220 | CPT | Destruction of localized lesion of choroid (e.g., choroidal neovascularization); photocoagulation | Not covered for drusen indications listed in CPB 0609 — classified experimental, investigational, or unproven |
Key ICD-10-CM Diagnosis Codes
These are the diagnosis codes Aetna lists in CPB 0609. Pairing CPT 67220 with any of these codes will trigger a claim denial under this coverage policy.
Age-Related Macular Degeneration
| Code | Description |
|---|---|
| H35.30–H35.3293 | Age-related macular degeneration (full code range) |
Macular Drusen
| Code | Description |
|---|---|
| H35.361 | Drusen (degenerative) of macula |
| H35.362 | Drusen (degenerative) of macula |
| H35.363 | Drusen (degenerative) of macula |
| H35.364 | Drusen (degenerative) of macula |
| H35.365 | Drusen (degenerative) of macula |
| H35.366 | Drusen (degenerative) of macula |
| H35.367 | Drusen (degenerative) of macula |
| H35.368 | Drusen (degenerative) of macula |
| H35.369 | Drusen (degenerative) of macula |
Drusen of Optic Disc
| Code | Description |
|---|---|
| H47.321 | Drusen of optic disc |
| H47.322 | Drusen of optic disc |
| H47.323 | Drusen of optic disc |
| H47.324 | Drusen of optic disc |
| H47.325 | Drusen of optic disc |
| H47.326 | Drusen of optic disc |
| H47.327 | Drusen of optic disc |
| H47.328 | Drusen of optic disc |
| H47.329 | Drusen of optic disc |
Choroidal Degeneration, Unspecified
| Code | Description |
|---|---|
| H31.101 | Choroidal degeneration, unspecified |
| H31.102 | Choroidal degeneration, unspecified |
| H31.103 | Choroidal degeneration, unspecified |
| H31.104 | Choroidal degeneration, unspecified |
| H31.105 | Choroidal degeneration, unspecified |
| H31.106 | Choroidal degeneration, unspecified |
| H31.107 | Choroidal degeneration, unspecified |
| H31.108 | Choroidal degeneration, unspecified |
| H31.109 | Choroidal degeneration, unspecified |
Age-Related Choroidal Atrophy
| Code | Description |
|---|---|
| H31.111 | Age-related choroidal atrophy |
| H31.112 | Age-related choroidal atrophy |
| H31.113 | Age-related choroidal atrophy |
| H31.114 | Age-related choroidal atrophy |
| H31.115 | Age-related choroidal atrophy |
| H31.116 | Age-related choroidal atrophy |
| H31.117 | Age-related choroidal atrophy |
| H31.118 | Age-related choroidal atrophy |
| H31.119 | Age-related choroidal atrophy |
Diffuse Secondary Atrophy of Choroid
| Code | Description |
|---|---|
| H31.121 | Diffuse secondary atrophy of choroid |
| H31.122 | Diffuse secondary atrophy of choroid |
| H31.123 | Diffuse secondary atrophy of choroid |
| H31.124 | Diffuse secondary atrophy of choroid |
| H31.125 | Diffuse secondary atrophy of choroid |
| H31.126 | Diffuse secondary atrophy of choroid |
| H31.127 | Diffuse secondary atrophy of choroid |
| H31.128 | Diffuse secondary atrophy of choroid |
| H31.129 | Diffuse secondary atrophy of choroid |
One more note on the code table: CPT 67220 has other clinical applications beyond drusen. Verify coverage status for non-drusen indications separately with Aetna. Don't let this policy's denial risk bleed into other CPT 67220 claim workflows. Keep your ICD-10 coding precise — the diagnosis code is what triggers the CPB 0609 exclusion.
Get the Full Picture for CPT 67220
Track this policy across versions, search 1,500+ policies by CPT code, and get real-time alerts when any payer changes coverage.