Aetna modified CPB 0604 for infrared therapy, effective December 4, 2025. Here's what billing teams need to know before submitting claims.
Aetna, a CVS Health company, updated CPB 0604 — its infrared therapy coverage policy — affecting CPT 46930 and 97026 on the covered side, and HCPCS E0221 and A4639 on the non-covered side. The policy draws a hard line between infrared coagulation (covered for specific anorectal conditions) and low-level infrared light therapy (not covered for nearly three dozen diagnoses). If your practice bills infrared therapy for anything outside anal dysplasia, grade I or II hemorrhoids, or physical therapy heat modalities, expect a claim denial.
Quick-Reference Table
| Field | Detail |
|---|---|
| Payer | Aetna, a CVS Health company |
| Policy | Infrared Therapy — CPB 0604 |
| Policy Code | CPB 0604 |
| Change Type | Modified |
| Effective Date | December 4, 2025 |
| Impact Level | Medium — high exposure for practices billing low-level infrared for wound care, neuropathy, or pain |
| Specialties Affected | Gastroenterology, colorectal surgery, physical therapy, wound care, neurology |
| Key Action | Audit active orders for CPT 97026, E0221, and A4639 against covered indications before submitting claims dated on or after December 4, 2025 |
Aetna Infrared Therapy Coverage Criteria and Medical Necessity Requirements 2025
The Aetna infrared therapy coverage policy under CPB 0604 splits infrared treatment into two distinct categories. Infrared coagulation gets covered. Low-level infrared light therapy does not — except as a heat modality in physical therapy.
Infrared coagulation (CPT 46930) meets medical necessity under two conditions:
| # | Covered Indication |
|---|---|
| 1 | Anal dysplasia |
| 2 | Grade I or grade II internal hemorrhoids that are painful or persistently bleeding |
That's it. Aetna's grading criteria for internal hemorrhoids appears in the policy appendix, so your documentation needs to specify hemorrhoid grade explicitly. A chart note that says "hemorrhoids" without grading will not satisfy these criteria.
CPT 97026 — application of infrared as a physical therapy modality — is covered when used as a heat modality in a physical therapy context. This is a narrow carve-out. The code is covered, but only when it's functioning as a heat modality within a broader physical therapy treatment plan. Billing 97026 for low-level infrared therapy outside that context puts you in experimental territory.
Aetna does not specify prior authorization requirements within CPB 0604 itself. That said, prior auth requirements vary by plan. Before scheduling infrared coagulation, verify authorization requirements at the individual plan level — especially for colorectal surgery cases.
Reimbursement for CPT 46930 depends on meeting both the diagnosis criteria and the hemorrhoid grading threshold. If you're billing for grade III or grade IV hemorrhoids, this policy doesn't support coverage under infrared coagulation.
Aetna Infrared Therapy Exclusions and Non-Covered Indications
This is where the policy gets extensive — and where most of your claim denial risk lives.
Aetna classifies low-level infrared light therapy (including the Anodyne Therapy System) as experimental, investigational, or unproven for 29 specific conditions. The list covers conditions that billing teams often assume have some coverage pathway. It doesn't.
The 29 excluded indications are:
| # | Excluded Procedure |
|---|---|
| 1 | Acne |
| 2 | Back pain (lumbar and thoracic) |
| 3 | Bell's palsy |
| 4 | Bone regeneration |
| 5 | Brain disorders (including dementia) |
| 6 | Calcaneal tendon injury |
| 7 | Cancer |
| 8 | Cardiovascular diseases |
| 9 | Central nervous system injuries |
| 10 | Chronic kidney diseases |
| 11 | Chronic non-healing wounds (including pressure ulcers) |
| 12 | Diabetes mellitus (including diabetic macular edema and diabetic peripheral neuropathy) |
| 13 | Disorders of consciousness |
| 14 | Ischemic stroke |
| 15 | Lymphedema |
| 16 | Migraines |
| 17 | Neck pain |
| 18 | Non-diabetic peripheral neuropathy |
| 19 | Onychomycosis |
| 20 | Osteoarthritis |
| 21 | Parkinson's disease |
| 22 | Retinal degeneration |
| 23 | Seasonal affective disorder (prevention) |
| 24 | Spinocerebellar ataxia |
| 25 | Stroke |
| 26 | Temporomandibular disorder |
| 27 | Tendinopathy |
| 28 | Traumatic brain injury |
| 29 | Xerostomia |
Wound care and neuropathy are the two highest-exposure areas here. Practices that bill low-level infrared for diabetic peripheral neuropathy or chronic non-healing wounds have been doing so under an assumption of coverage that this policy explicitly rejects. That gap matters.
Two additional exclusions apply:
| # | Excluded Procedure |
|---|---|
| 1 | The infrared glove (e.g., Prolotex Therapy Glove) is not covered for Raynaud's syndrome or any other indication |
| 2 | Photo-biomodulation using infrared light-emitting diode is not covered for asthma |
HCPCS codes E0221 (infrared heating pad system) and A4639 (replacement pad for infrared heating pad system) are not covered for any of the indications listed in CPB 0604. If you have durable medical equipment suppliers billing these codes for home-use infrared devices, those claims will not clear under this policy.
Coverage Indications at a Glance
| Indication | Status | Relevant Codes | Notes |
|---|---|---|---|
| Anal dysplasia | Covered | CPT 46930 | Medical necessity criteria apply |
| Grade I or II internal hemorrhoids (painful or persistently bleeding) | Covered | CPT 46930 | Grade must be documented in chart; see policy appendix |
| Infrared as heat modality in physical therapy | Covered | CPT 97026 | Covered only within PT treatment context |
| Chronic non-healing wounds / pressure ulcers | Experimental | — | Low-level infrared not covered |
| Diabetic peripheral neuropathy | Experimental | — | Includes Anodyne Therapy System |
| Diabetic macular edema | Experimental | — | Diabetes mellitus category |
| Non-diabetic peripheral neuropathy | Experimental | — | Explicitly excluded |
| Back pain (lumbar and thoracic) | Experimental | — | Low-level infrared not covered |
| Neck pain | Experimental | — | Low-level infrared not covered |
| Osteoarthritis | Experimental | — | Low-level infrared not covered |
| Tendinopathy | Experimental | — | Includes calcaneal tendon injury |
| Lymphedema | Experimental | — | Low-level infrared not covered |
| Traumatic brain injury | Experimental | — | Includes related brain disorders |
| Parkinson's disease | Experimental | — | Low-level infrared not covered |
| Onychomycosis | Experimental | — | Low-level infrared not covered |
| Raynaud's syndrome | Not Covered | — | Infrared glove specifically excluded |
| Asthma | Not Covered | — | Photo-biomodulation via LED excluded |
| Cancer | Experimental | — | All malignant neoplasms excluded |
| Cardiovascular diseases | Experimental | — | Broad category exclusion |
| Infrared heating pad system (home use) | Not Covered | HCPCS E0221, A4639 | No covered indications under this policy |
Aetna Infrared Therapy Billing Guidelines and Action Items 2025
The effective date of December 4, 2025 is already here. These actions apply to claims you're submitting now.
| # | Action Item |
|---|---|
| 1 | Audit all active infrared therapy orders against CPB 0604's covered indications. Pull any open orders for low-level infrared therapy — especially for diabetic neuropathy, wound care, or pain diagnoses. Claims for those services submitted with dates of service on or after December 4, 2025 will not meet medical necessity under this policy. |
| 2 | Check hemorrhoid grading documentation before billing CPT 46930. Aetna covers infrared coagulation for grade I and grade II internal hemorrhoids only. Your procedure notes need to specify the hemorrhoid grade explicitly. Missing or vague documentation is the fastest path to a denied claim on this code. |
| 3 | Review CPT 97026 claims for context. The code is covered — but only as a heat modality within physical therapy. If your billing team is using 97026 for low-level infrared therapy sessions outside a formal PT plan, reclass those before submission. |
| 4 | Pull any HCPCS E0221 and A4639 claims in your queue. These codes — infrared heating pad system and replacement pads — have no covered indications under this policy. If you have DME suppliers or home care partners billing these under Aetna for any of the 29 excluded diagnoses, those claims will deny. |
| 5 | Flag anal dysplasia cases for CPT 46930 coverage. This is a covered indication that often gets undercoded or miscoded. If your gastroenterology or colorectal surgery team treats anal dysplasia with infrared coagulation, confirm your charge capture includes CPT 46930 with the appropriate ICD-10 diagnosis code. |
| 6 | Talk to your compliance officer if your practice regularly bills low-level infrared therapy for wound care or neuropathy. This policy's experimental designation covers a wide range of diagnoses. If low-level infrared is part of your standard wound care or pain management protocol, the financial exposure is real. Get a formal review before you keep billing it under Aetna plans. |
| 7 | Confirm prior authorization requirements at the plan level for CPT 46930. CPB 0604 doesn't specify prior auth requirements, but individual Aetna plans may. Verify before the procedure — not after. |
| Previous Version | Current Version |
|---|---|
| Coverage is considered experimental and investigational for all indications | Coverage is considered medically necessary when specific criteria are met |
| Prior authorization is not required | Prior authorization is required for initial treatment |
| Documentation must include clinical history | Documentation must include clinical history |
| Re-review every 24 months | Re-review every 12 months with updated clinical documentation |
CPT, HCPCS, and ICD-10 Codes for Infrared Therapy Under CPB 0604
Covered CPT Codes (When Selection Criteria Are Met)
| Code | Type | Description |
|---|---|---|
| 46930 | CPT | Destruction of internal hemorrhoid(s), by thermal energy (e.g., infrared coagulation, cautery, radiofrequency) |
| 97026 | CPT | Application of a modality to one or more areas; infrared |
Not Covered / Non-Covered HCPCS Codes
| Code | Type | Description | Reason |
|---|---|---|---|
| A4639 | HCPCS | Replacement pad for infrared heating pad system, each | Not covered for indications listed in CPB 0604 |
| E0221 | HCPCS | Infrared heating pad system | Not covered for indications listed in CPB 0604 |
Key ICD-10-CM Diagnosis Codes
These codes appear in CPB 0604's covered and non-covered code sets. The table below focuses on the highest-volume diagnoses most likely to appear in your billing queue.
| Code / Range | Description | Coverage Status Under CPB 0604 |
|---|---|---|
| B35.1 | Tinea unguium (onychomycosis) | Not covered — experimental for low-level infrared |
| C00.0–D09.9 | Malignant neoplasms and carcinoma in situ | Not covered — experimental for low-level infrared |
| E08.00–E13.9 | Diabetes mellitus (all types) | Not covered — includes diabetic neuropathy and macular edema |
| F01.50–F01.C4 | Vascular dementia | Not covered — brain disorders excluded |
| F02.80–F02.818 | Dementia in other diseases classified elsewhere | Not covered — brain disorders excluded |
| F03.90–F03.918 | Unspecified dementia | Not covered — brain disorders excluded |
| F33.0–F33.9 | Major depressive disorder, recurrent | Not covered for prevention of seasonal affective disorder |
| G11.11–G11.19 | Early-onset cerebellar ataxia (spinocerebellar ataxia) | Not covered — experimental for low-level infrared |
| G20.A1–G21.9 | Parkinson's disease | Not covered — experimental for low-level infrared |
| G43.001–G43.901 | Migraines | Not covered — experimental for low-level infrared |
| G51.0 | Bell's palsy | Not covered — experimental for low-level infrared |
| G60.0–G62.9 | Non-diabetic peripheral neuropathy | Not covered — experimental for low-level infrared |
| G91.0–G91.9 | Hydrocephalus | Not covered — central nervous system category |
| G92.0–G92.5 | Toxic encephalopathy | Not covered — brain disorders excluded |
| G93.1–G93.9 | Other disorders of brain | Not covered — brain disorders excluded |
| H35.30–H35.469 | Degeneration of macula and posterior pole; peripheral retinal degeneration | Not covered — retinal degeneration excluded |
| I00–I99 range | Cardiovascular diseases (rheumatic, hypertensive, ischemic heart disease, stroke) | Not covered — cardiovascular diseases excluded |
The full ICD-10 code set for CPB 0604 includes 415 codes. Review the complete list at app.payerpolicy.org/p/aetna/0604 before building out your denial management rules.
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