TL;DR: Aetna, a CVS Health company, modified CPB 0584 — its mammography coverage policy — effective September 26, 2025. Here's what billing teams need to do before claims start hitting the new criteria.
This update to CPB 0584 Aetna's mammography policy touches CPT codes 77061, 77062, 77063, 77065, 77066, 77067, and HCPCS code G0279. The policy covers screening and diagnostic mammography across a broader population than many billing teams realize — including BRCA-positive men, transfeminine patients, and younger women with specific hereditary syndromes. If your charge capture isn't built around these criteria, you're either leaving reimbursement on the table or heading toward a claim denial.
Quick-Reference Table
| Field | Detail |
|---|---|
| Payer | Aetna |
| Policy | Mammography — CPB 0584 |
| Policy Code | CPB 0584 |
| Change Type | Modified |
| Effective Date | September 26, 2025 |
| Impact Level | High |
| Specialties Affected | Radiology, OB/GYN, Breast Surgery, Oncology, Primary Care |
| Key Action | Audit your charge capture for CPT 77061–77067 and G0279 against the updated medical necessity criteria before billing claims with a September 26, 2025 or later date of service |
Aetna Mammography Coverage Criteria and Medical Necessity Requirements 2025
The Aetna mammography coverage policy under CPB 0584 is organized around who qualifies for screening versus diagnostic services. Knowing the difference matters, because diagnostic mammography (CPT 77065 and 77066) carries different documentation requirements than screening.
Standard Screening — Women 40 and Older
Annual screening mammography, billed with CPT 77067, is considered medically necessary for all women aged 40 and older. No additional diagnosis codes or documentation of elevated risk are required at the standard threshold.
High-Risk Screening — Women Under 40
Younger women qualify for annual screening under five specific conditions. Aetna covers screening mammography for patients who are:
| # | Covered Indication |
|---|---|
| 1 | BRCA1 or BRCA2 mutation carriers |
| 2 | Women who meet the criteria for BRCA mutation testing per CPB 0227 |
| 3 | Women with a personal diagnosis of Bannayan-Riley-Ruvalcaba syndrome, Cowden syndrome, or Li-Fraumeni syndrome |
| 4 | Women with a first-degree relative diagnosed with one of those syndromes |
| 5 | Women with a personal history of radiation to the chest between ages 10 and 30 |
For these patients, document the qualifying condition explicitly. Use the appropriate ICD-10-CM code from the hereditary neoplasm or personal history code ranges — Aetna's coverage policy is clear that the diagnosis or history must support the claim.
BRCA-Positive Men
This is where a lot of billing teams miss claims. Aetna considers annual screening mammography medically necessary for BRCA-positive men with gynecomastia. Coverage starts at age 50, or 10 years before the earliest known male breast cancer in the family — whichever comes first.
If your practice sees male breast patients, make sure your charge capture handles this population. Billing 77067 on a male patient will raise a flag without the right diagnosis coding and documentation to support it.
Transfeminine Patients
Aetna covers screening mammography for transfeminine (male-to-female) persons who are 40 or older and have used hormones for five or more years. This is a population that generates frequent prior authorization questions. The policy is clear: medical necessity is met when both the age and the duration of hormone use are documented.
If your practice serves this population and you're not capturing hormone use duration in your documentation workflow, fix that now. A claim denial on this basis is avoidable.
Diagnostic Mammography
CPT 77065 (unilateral) and 77066 (bilateral) cover diagnostic mammography for any member — women or men — with signs or symptoms of breast disease, or a history of breast cancer. Aetna explicitly states that diagnostic mammography is covered regardless of whether the member has preventive services benefits.
That last sentence matters. Don't assume a patient's plan exclusions for preventive services block diagnostic mammography billing. They don't, under this coverage policy.
3D Mammography and CAD
Aetna considers digital breast tomosynthesis (CPT 77061, 77062, 77063, and HCPCS G0279) an acceptable alternative to standard 2D mammography. Computer-aided detection (CAD) is considered a medically necessary adjunct — meaning you don't need a separate justification to bill it alongside the primary mammography code. The CAD component is already bundled into CPT 77065, 77066, and 77067 per the code descriptors.
Coverage Indications at a Glance
| Indication | Status | Relevant Codes | Notes |
|---|---|---|---|
| Annual screening, women 40+ | Covered | 77067 | No elevated risk required |
| Annual screening, women under 40 with BRCA1/2 mutation | Covered | 77067 | Document mutation status |
| Annual screening, women under 40 meeting CPB 0227 BRCA testing criteria | Covered | 77067 | Cross-reference CPB 0227 criteria |
| Annual screening, women with Bannayan-Riley-Ruvalcaba, Cowden, or Li-Fraumeni syndrome (personal or first-degree relative) | Covered | 77067 | Document syndrome diagnosis or family history |
| Annual screening, women with chest radiation history ages 10–30 | Covered | 77067 | Document radiation history in chart |
| Annual screening, BRCA-positive men with gynecomastia (age 50+ or 10 years before earliest family male breast cancer) | Covered | 77067 | Document BRCA status, gynecomastia, and qualifying age |
| Screening mammography, transfeminine patients 40+ with ≥5 years hormone use | Covered | 77067 | Document hormone use duration |
| Diagnostic mammography, signs/symptoms or history of breast cancer (women and men) | Covered | 77065, 77066 | Covered regardless of preventive benefit status |
| Digital breast tomosynthesis (3D mammography) | Covered | 77061, 77062, 77063, G0279 | Acceptable alternative to 2D; selection criteria apply |
| Computer-aided detection (CAD) as adjunct to mammography | Covered | Bundled in 77065, 77066, 77067 | Medically necessary adjunct; no separate justification needed |
| Digital mammography | Covered | Applicable mammography CPTs | Acceptable alternative to film |
Aetna Mammography Billing Guidelines and Action Items 2025
The effective date is September 26, 2025. If you haven't already audited your workflows against this updated policy, do it now.
| # | Action Item |
|---|---|
| 1 | Audit your charge capture for CPT 77061, 77062, 77063, 77065, 77066, 77067, and G0279. Confirm that each code maps to the correct indication in your charge master. 3D tomosynthesis codes and the diagnostic codes are the most common misfire points. |
| 2 | Update your documentation templates for high-risk and non-standard populations. For BRCA-positive men, transfeminine patients, and women under 40, the medical necessity justification must appear in the chart before the claim goes out. If your templates don't prompt for BRCA status, hormone use duration, or hereditary syndrome history, they need to. |
| 3 | Train your front-end staff on the transfeminine and male breast patient criteria. These populations generate the most prior authorization confusion. Your team needs to know that hormone use duration (five or more years) and age (40+) are the two triggers for coverage — and that documentation of both is required. |
| 4 | Stop assuming preventive benefit exclusions block diagnostic mammography claims. CPT 77065 and 77066 are covered under this Aetna coverage policy regardless of preventive services benefit design. If your team has been writing off these claims for members with limited preventive benefits, audit the last 12 months of remittances for that population. |
| 5 | Verify your CAD billing approach. CAD is bundled into the descriptors for 77065, 77066, and 77067. Don't bill it separately — that's a path to a claim denial or a fraud and abuse flag. If your billing guidelines still reference a separate CAD add-on code, remove it. |
| 6 | Check prior authorization requirements at the plan level. CPB 0584 establishes medical necessity criteria, but individual Aetna plan designs may still require prior authorization for specific services. Screening mammography for standard-risk patients typically doesn't require prior auth, but 3D tomosynthesis (G0279 especially) can trigger plan-level requirements. Verify before scheduling for high-cost configurations. If you're unsure how this applies to your payer mix, talk to your compliance officer before billing under the new criteria. |
| Previous Version | Current Version |
|---|---|
| Coverage is considered experimental and investigational for all indications | Coverage is considered medically necessary when specific criteria are met |
| Prior authorization is not required | Prior authorization is required for initial treatment |
| Documentation must include clinical history | Documentation must include clinical history |
| Re-review every 24 months | Re-review every 12 months with updated clinical documentation |
CPT, HCPCS, and ICD-10 Codes for Mammography Under CPB 0584
Covered CPT Codes (When Selection Criteria Are Met)
| Code | Type | Description |
|---|---|---|
| 77061 | CPT | Digital breast tomosynthesis, unilateral |
| 77062 | CPT | Digital breast tomosynthesis, bilateral |
| 77063 | CPT | Screening digital breast tomosynthesis, bilateral (list separately in addition to code for primary procedure) |
| 77065 | CPT | Diagnostic mammography, including computer-aided detection (CAD) when performed; unilateral |
| 77066 | CPT | Diagnostic mammography, including computer-aided detection (CAD) when performed; bilateral |
| 77067 | CPT | Screening mammography, bilateral (2-view study of each breast), including computer-aided detection (CAD) when performed |
Covered HCPCS Codes (When Selection Criteria Are Met)
| Code | Type | Description |
|---|---|---|
| G0279 | HCPCS | Diagnostic digital breast tomosynthesis, unilateral or bilateral (list separately in addition to 77065 or 77066) |
Key ICD-10-CM Diagnosis Codes
| Code | Description |
|---|---|
| C50.011–C50.929 | Malignant neoplasm of breast |
| C79.81 | Secondary malignant neoplasm of breast |
| D05.0 | Carcinoma in situ of breast |
| D05.10–D05.19 | Lobular carcinoma in situ of breast |
| D05.20–D05.29 | Carcinoma in situ of breast, intraductal |
| D05.30–D05.39 | Carcinoma in situ of breast |
| D05.40–D05.49 | Carcinoma in situ of breast |
| D05.50–D05.59 | Carcinoma in situ of breast |
| D05.60–D05.69 | Carcinoma in situ of breast |
| D05.70–D05.79 | Carcinoma in situ of breast |
The full ICD-10-CM code list under CPB 0584 contains 122 codes spanning malignant breast neoplasms, carcinoma in situ, and related diagnoses. Pull the complete list from the source policy before updating your charge capture — partial ICD-10 mapping is one of the most common causes of unnecessary claim denial on mammography claims.
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