Aetna modified CPB 0480 for Tourette syndrome assessment and treatment, effective February 27, 2026. Here's what billing teams need to know.
Aetna, a CVS Health company, updated Clinical Policy Bulletin CPB 0480 governing the Aetna Tourette syndrome coverage policy for assessment and treatment services. The change affects a wide range of CPT codes — from EEG codes 95812 through 95830, to E&M codes 99201–99215, to psychotherapy codes 90832 and 90839. If your practice sees pediatric neurology, child psychiatry, or behavioral health patients with TS, this policy update directly affects your reimbursement.
Quick-Reference Table
| Field | Detail |
|---|---|
| Payer | Aetna, a CVS Health company |
| Policy | Tourette Syndrome — CPB 0480 |
| Policy Code | CPB 0480 |
| Change Type | Modified |
| Effective Date | February 27, 2026 |
| Impact Level | Medium |
| Specialties Affected | Pediatric neurology, child psychiatry, behavioral health, primary care |
| Key Action | Audit your TS claims against all five medical necessity criteria before billing covered CPT codes |
Aetna Tourette Syndrome Coverage Criteria and Medical Necessity Requirements 2026
The Aetna Tourette syndrome coverage policy under CPB 0480 sets five criteria that all must be met before any assessment or treatment service qualifies as medically necessary. Every single one. This is a conjunctive standard — missing one criteria means the claim is exposed.
Here's what Aetna requires:
| # | Covered Indication |
|---|---|
| 1 | The member has both multiple motor tics and one or more vocal tics at some point during the illness (not necessarily at the same time) |
| 2 | The condition causes significant distress or marked impairment in social, occupational, or other important functioning |
| 3 | The tics are not caused by a substance (e.g., stimulants) or another medical condition (e.g., Huntington's disease or post-viral encephalitis) |
| 4 | Onset occurred before age 21 |
| 5 | Tics occur many times daily (usually in bouts) almost every day, or periodically, over more than one year — with no tic-free period exceeding three consecutive months |
That fifth criterion is the one that trips up documentation most often. "More than one year" with no long break is a high bar. If your clinical notes don't explicitly address duration and frequency, you'll face a claim denial.
Once medical necessity is established, two categories of services become billable. For assessment, Aetna covers a complete medical history and physical examination, and EEG codes (95812–95830) — but only when focal neurological signs or clinical suspicion of seizure disorder or a degenerative condition are present. EEGs aren't routine workup tools under this policy. If you're billing 95812 or 95816 without documented focal signs, that claim is vulnerable.
For treatment, covered pharmacotherapies include aripiprazole (Abilify), clonazepam (Klonopin), clonidine (Catapres), fluphenazine (Prolixin), haloperidol (Haldol), pimozide (Orap), risperidone (Risperdal), tetrabenazine, and tricyclic antidepressants when ADHD is comorbid. Note that these are pharmacy benefit items — they're subject to formulary restrictions. Check the member's plan before assuming coverage.
Psychotherapy (CPT 90832, 90838, 90839, 90840, and add-on +90785) is covered when the member also exhibits anxiety or depression. It falls under behavioral health benefits, not medical. Your billing team should confirm which benefit bucket applies before submitting claims.
Prior authorization requirements are not explicitly stated in this policy bulletin. That doesn't mean prior auth isn't required for your member's specific plan. Check individual plan benefit descriptions before scheduling high-cost services.
Aetna Tourette Syndrome Exclusions and Non-Covered Indications
This section is where the real billing risk lives. Aetna classifies a long list of services as experimental, investigational, or unproven for TS. Billing these will generate a claim denial.
On the assessment side, Aetna won't cover:
| # | Excluded Procedure |
|---|---|
| 1 | Cognitive and motor event-related potentials |
| 2 | Computerized EEG or brain mapping (see CPB 0221) |
| 3 | Genetic studies (CPT 88245 and related codes) |
| 4 | Plasma or serum cytokines and T-cell measurements |
| 5 | Serum ferritin level (CPT 82728) |
| 6 | MicroRNAs as biomarkers |
| 7 | Neuroimaging — CT (70450, 70460, 70470), MRI (70551, 70552, 70553), PET (78608, 78609), and SPECT (78607) |
| 8 | Quantitative susceptibility mapping for brain iron (CPT 0648T, 0649T) |
That neuroimaging exclusion is significant. Brain MRIs and CT scans are common in neurological workups, and it's easy to assume they'd be covered. For TS under this policy, they're not — regardless of how thorough the clinical rationale.
On the treatment side, Aetna will not cover:
| # | Excluded Procedure |
|---|---|
| 1 | Acupuncture (see CPB 0135) |
| 2 | Adaptive (responsive) deep brain stimulation |
| 3 | Amphetamines (unless comorbid ADHD is documented) |
| 4 | Anti-glutamatergic drugs including gabapentin, lamotrigine, riluzole, and topiramate |
| 5 | Baclofen |
| 6 | Bilateral stereotactic lesions of the anterior cingulate gyrus |
| 7 | Bilateral thalamic stimulation and standard deep brain stimulation (CPT 61863, 61864, 61867, 61868 — see CPB 0208) |
| 8 | Botox injections (CPT 64612, 64616, 64617 — see CPB 0113) |
If your practice offers deep brain stimulation or botulinum toxin for tic management, do not bill those services under this TS diagnosis without a clear plan. They're excluded under CPB 0480.
Coverage Indications at a Glance
| Indication | Status | Relevant Codes | Notes |
|---|---|---|---|
| Complete medical history and physical exam | Covered | 99201–99215 | All five selection criteria must be met |
| EEG for TS with focal signs or seizure suspicion | Covered | 95812–95830 | Only when focal neurological signs or seizure/degenerative condition suspected |
| Pharmacotherapy (aripiprazole, clonidine, haloperidol, pimozide, risperidone, tetrabenazine, etc.) | Covered | Pharmacy benefit | Formulary restrictions may apply; verify per plan |
| Tricyclic antidepressants | Covered | Pharmacy benefit | Only when comorbid ADHD is documented |
| Psychotherapy for comorbid anxiety or depression | Covered | 90832, 90838, 90839, 90840, +90785 | Behavioral health benefit; verify with member plan |
| Neuroimaging (CT, MRI, PET, SPECT) | Not Covered — Experimental | 70450, 70460, 70470, 70551–70553, 78607, 78608, 78609 | Considered experimental/investigational for TS |
| Computerized EEG / brain mapping | Not Covered — Experimental | See CPB 0221 | Cross-reference CPB 0221 |
| Genetic studies | Not Covered — Experimental | 88245 and related | Insufficient evidence for TS |
| Serum ferritin measurement | Not Covered — Experimental | 82728 | Considered experimental for TS |
| Deep brain stimulation | Not Covered — Experimental | 61863, +61864, 61867, +61868, 61880, 61885, 61886, 61888 | See CPB 0208 |
| Botulinum toxin injections | Not Covered — Experimental | 64612, 64616, 64617 | See CPB 0113 |
| Acupuncture | Not Covered — Experimental | See CPB 0135 | See CPB 0135 |
| Amphetamines | Not Covered — Experimental | — | Covered only if comorbid ADHD documented |
| Anti-glutamatergic drugs (gabapentin, lamotrigine, riluzole, topiramate) | Not Covered — Experimental | Pharmacy benefit | Not covered for TS indication |
| Baclofen | Not Covered — Experimental | Pharmacy benefit | Not covered for TS indication |
| Quantitative susceptibility mapping | Not Covered — Experimental | 0648T, 0649T | New entry — watch for denials |
| Transcranial direct current stimulation | Not Covered — Experimental | Multiple codes | See Affected Codes section |
| Stereotactic lesioning of anterior cingulate gyrus | Not Covered — Experimental | 61735 | Bilateral approach excluded |
Aetna Tourette Syndrome Billing Guidelines and Action Items 2026
The effective date for this modified policy is February 27, 2026. If you haven't reviewed your TS claims workflow against the updated CPB 0480 criteria yet, do it now.
| # | Action Item |
|---|---|
| 1 | Audit your documentation templates against all five medical necessity criteria. Every TS claim needs documentation covering: tic type (motor and vocal), functional impairment, exclusion of substance or medical causes, age of onset before 21, and duration over one year with no tic-free break exceeding three months. If your templates don't capture all five, update them before submitting Aetna claims. |
| 2 | Stop billing EEG codes (95812–95830) as routine TS workup. Aetna only covers EEGs when focal neurological signs are present or a seizure or degenerative condition is clinically suspected. If your physicians order EEGs as standard practice for new TS diagnoses, that's a claim denial waiting to happen. |
| 3 | Reclassify psychotherapy to behavioral health benefits. CPT codes 90832, 90838, 90839, 90840, and +90785 for comorbid anxiety and depression fall under behavioral health — not medical. Route those claims correctly. Wrong benefit bucket = wrong payer address = denial. |
| 4 | Flag deep brain stimulation and botulinum toxin claims for TS diagnoses. If your practice bills CPT 61863, 61867, 64612, 64616, or 64617 for Tourette syndrome, those will deny under this policy. These are experimental under CPB 0480. If you believe a patient has a documented clinical exception, loop in your compliance officer before submitting. |
| 5 | Don't bill neuroimaging as part of a standard TS assessment. CT (70450–70470), MRI (70551–70553), PET (78608, 78609), and SPECT (78607) are all excluded under this policy. If neuroimaging is clinically necessary for another diagnosis, bill it under that separate indication — not as part of TS management. |
| 6 | Check amphetamine coverage carefully. Amphetamines are excluded for TS unless comorbid ADHD is documented. If your physician prescribes stimulants to a TS patient, the ADHD diagnosis must appear on the claim and in the medical record. Missing that documentation turns a covered service into a denial. |
| 7 | Verify prior auth requirements at the plan level. This coverage policy doesn't list specific prior authorization triggers, but individual Aetna plans may. Don't assume silence means no prior auth is needed. Call Aetna or use the member's plan documents to confirm before scheduling high-cost services. |
| Previous Version | Current Version |
|---|---|
| Coverage is considered experimental and investigational for all indications | Coverage is considered medically necessary when specific criteria are met |
| Prior authorization is not required | Prior authorization is required for initial treatment |
| Documentation must include clinical history | Documentation must include clinical history |
| Re-review every 24 months | Re-review every 12 months with updated clinical documentation |
CPT, HCPCS, and ICD-10 Codes for Tourette Syndrome Under CPB 0480
Covered CPT Codes (When Selection Criteria Are Met)
| Code | Description |
|---|---|
| +90785 | Interactive complexity (add-on to primary procedure) |
| 90832 | Psychotherapy, 30 minutes with patient and/or family member |
| 90838 | Psychotherapy, 60 minutes with patient and/or family member (with E&M) |
| 90839 | Psychotherapy for crisis; first 60 minutes |
| 90840 | Psychotherapy for crisis; each additional 30 minutes (add-on) |
| 95812 | Routine electroencephalography |
| 95813 | Routine electroencephalography |
| 95814 | Routine electroencephalography |
| 95815 | Routine electroencephalography |
| 95816 | Routine electroencephalography |
| 95817 | Routine electroencephalography |
| 95818 | Routine electroencephalography |
| 95819 | Routine electroencephalography |
| 95820 | Routine electroencephalography |
| 95821 | Routine electroencephalography |
| 95822 | Routine electroencephalography |
| 95823 | Routine electroencephalography |
| 95824 | Routine electroencephalography |
| 95825 | Routine electroencephalography |
| 95826 | Routine electroencephalography |
| 95827 | Routine electroencephalography |
| 95828 | Routine electroencephalography |
| 95829 | Routine electroencephalography |
| 95830 | Routine electroencephalography |
| 99201 | E&M, office or other outpatient services |
| 99202 | E&M, office or other outpatient services |
| 99203 | E&M, office or other outpatient services |
| 99204 | E&M, office or other outpatient services |
| 99205 | E&M, office or other outpatient services |
| 99206 | E&M, office or other outpatient services |
| 99207 | E&M, office or other outpatient services |
| 99208 | E&M, office or other outpatient services |
| 99209 | E&M, office or other outpatient services |
| 99210 | E&M, office or other outpatient services |
| 99211 | E&M, office or other outpatient services |
| 99212 | E&M, office or other outpatient services |
| 99213 | E&M, office or other outpatient services |
| 99214 | E&M, office or other outpatient services |
| 99215 | E&M, office or other outpatient services |
Other CPT Codes Related to CPB 0480
| Code | Description |
|---|---|
| 96372 | Therapeutic, prophylactic, or diagnostic injection; subcutaneous or intramuscular |
Not Covered / Experimental CPT Codes
| Code | Description | Basis for Exclusion |
|---|---|---|
| 00140 | Anesthesia for procedures on eye; not otherwise specified | Experimental for TS |
| 0042T | Cerebral perfusion analysis using CT with contrast | Experimental for TS |
| 0648T | Quantitative MR for tissue composition analysis | Experimental — quantitative susceptibility mapping |
| 0649T | Quantitative MR for tissue composition analysis | Experimental — quantitative susceptibility mapping |
| 61735 | Stereotactic lesion creation with burr hole(s) | Experimental — bilateral stereotactic lesions |
| 61863 | Stereotactic implantation of neurostimulator electrode(s) | Experimental — deep brain stimulation |
| +61864 | Each additional neurostimulator array (add-on) | Experimental — deep brain stimulation |
| 61867 | Stereotactic implantation of neurostimulator electrode(s), computer-assisted | Experimental — deep brain stimulation |
| +61868 | Each additional array, computer-assisted (add-on) | Experimental — deep brain stimulation |
| 61880 | Revision or removal of intracranial neurostimulator electrodes | Experimental — deep brain stimulation |
| 61885 | Insertion or replacement of cranial neurostimulator pulse generator or receiver | Experimental — deep brain stimulation |
| 61886 | Insertion or replacement of cranial neurostimulator pulse generator or receiver (multiple) | Experimental — deep brain stimulation |
| 61888 | Revision or removal of cranial neurostimulator pulse generator or receiver | Experimental — deep brain stimulation |
| 64612 | Chemodenervation of facial muscle(s), unilateral | Experimental — botulinum toxin for TS |
| 64616 | Chemodenervation of neck muscle(s), excluding larynx, unilateral | Experimental — botulinum toxin for TS |
| 64617 | Chemodenervation of larynx, unilateral, percutaneous | Experimental — botulinum toxin for TS |
| 70450 | CT head or brain; without contrast | Experimental — neuroimaging for TS |
| 70460 | CT head or brain; with contrast | Experimental — neuroimaging for TS |
| 70470 | CT head or brain; without then with contrast | Experimental — neuroimaging for TS |
| 70472 | CT cerebral perfusion analysis with contrast | Experimental — neuroimaging for TS |
| 70473 | CT cerebral perfusion analysis with contrast (additional) | Experimental — neuroimaging for TS |
| 70496 | CT angiography, head | Experimental — neuroimaging for TS |
| 70544 | MR angiography, head; without contrast | Experimental — neuroimaging for TS |
| 70545 | MR angiography, head; with contrast | Experimental — neuroimaging for TS |
| 70546 | MR angiography, head; without then with contrast | Experimental — neuroimaging for TS |
| 70551 | MRI, brain; without contrast | Experimental — neuroimaging for TS |
| 70552 | MRI, brain; with contrast | Experimental — neuroimaging for TS |
| 70553 | MRI, brain; without then with contrast | Experimental — neuroimaging for TS |
| 70554 | Functional MRI, brain | Experimental — neuroimaging for TS |
| 70555 | Functional MRI, brain; physician/psychologist-administered | Experimental — neuroimaging for TS |
| 78600 | Brain imaging, less than 4 static views | Experimental — neuroimaging for TS |
| 78601 | Brain imaging with vascular flow | Experimental — neuroimaging for TS |
| 78605 | Brain imaging; minimum 4 static views | Experimental — neuroimaging for TS |
| 78606 | Brain imaging; minimum 4 static views with vascular flow | Experimental — neuroimaging for TS |
| 78607 | Brain imaging, tomographic (SPECT) | Experimental — neuroimaging for TS |
| 78608 | Brain PET; metabolic evaluation | Experimental — neuroimaging for TS |
| 78609 | Brain PET; perfusion evaluation | Experimental — neuroimaging for TS |
| 78610 | Brain imaging, vascular flow only | Experimental — neuroimaging for TS |
| 82728 | Ferritin | Experimental — serum ferritin for TS |
| 88245 | Chromosome analysis | Experimental — genetic studies for TS |
Note: The full policy data references 145 CPT codes total. The policy source lists additional codes beyond what appears in the truncated data extract. Review the full CPB 0480 document at Aetna's policy portal to confirm all applicable codes for your practice.
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