Aetna modified CPB 0393 for vitrectomy, effective September 26, 2025. Here's what changes for billing teams.
Aetna, a CVS Health company, updated its vitrectomy coverage policy under CPB 0393 in the Aetna system, clarifying medical necessity criteria across 12 covered indications and adding explicit coverage for post-vitrectomy face support devices. The update affects CPT codes 67036 through 67043 — the core pars plana vitrectomy code family — along with related retinal repair codes 67108 and 67113. If your practice bills for retinal surgery under Aetna plans, review your charge capture and documentation protocols now.
Quick-Reference Table
| Field | Detail |
|---|---|
| Payer | Aetna, a CVS Health company |
| Policy | Vitrectomy — CPB 0393 |
| Policy Code | CPB 0393 in the Aetna system |
| Change Type | Modified |
| Effective Date | September 26, 2025 |
| Impact Level | Medium |
| Specialties Affected | Ophthalmology, Retinal Surgery, Vitreoretinal Surgery |
| Key Action | Audit active Aetna claims for vitrectomy billing against the updated 12-indication criteria list, and add face support device coverage to your post-op billing workflows |
Aetna Vitrectomy Coverage Criteria and Medical Necessity Requirements 2025
The updated Aetna vitrectomy coverage policy under CPB 0393 defines 12 specific conditions where vitrectomy meets medical necessity. This is a tighter framework than many billing teams assume. Aetna does not cover vitrectomy as a general surgical option — the diagnosis must map cleanly to one of the covered indications.
Here are the 12 covered conditions:
| # | Covered Indication |
|---|---|
| 1 | Epiretinal membrane with progression or worsening of vision — the qualifier matters. An epiretinal membrane diagnosis alone (H35.371–H35.379) does not clear the bar. You need documented progression or vision deterioration. |
| 2 | Macular hole repair (H35.341–H35.349) |
| 3 | Proliferative retinopathy, including diabetic proliferative retinopathy (E10.311–E10.39, E11.311–E11.39) |
| 4 | Rapidly progressing infectious endophthalmitis (H44.1–H44.2) |
| 5 | Removal of silicone oil used in retinal detachment treatment |
| 6 | Retinal detachments secondary to vitreous strands (H33.1–H33.8) |
| 7 | RPE65 mutation-associated retinal dystrophy (H35.50) — note that administration of voretigene neparvovec-rzyl (Luxturna) is handled under CPB 0927, not this policy |
| 8 | Traumatic penetrating ocular injury |
| 9 | Vitreous loss incident to cataract surgery (H43.89–H43.9) |
| 10 | Vitreoretinal lymphoma (C69.20–C69.22, C85.11, C85.91) |
| 11 | Vitreous membranes, strands, and opacities due to vitreous hemorrhage or other causes (H43.10–H43.13, H43.311–H43.319) |
| 12 | Vitreous retraction (H43.89–H43.9) |
The policy also covers a vitrectomy face support device — a post-vitrectomy face-down positioning system — when the patient has undergone vitrectomy and the surgeon requires post-operative face-down positioning. This is a practical addition that has reimbursement implications for DME suppliers and surgical facilities billing for post-op support equipment.
This policy does not specify prior authorization requirements. Verify prior authorization requirements directly with Aetna for each procedure.
Aetna Vitrectomy Exclusions and Non-Covered Indications
The not-covered CPT codes in this policy are worth flagging because they represent cataract surgery codes — and that's where billing errors happen. Aetna's CPB 0393 explicitly lists CPT 66850, 66852, 66982, 66984, 66987, 66988, 66989, and 66991 as not covered for the indications listed in this policy.
This makes clinical sense: those are cataract extraction and lens implant codes, not vitrectomy codes. But the risk is real. When a vitrectomy is performed in combination with cataract surgery — a common scenario — your team may be tempted to bill both procedure families together. Under this policy, the cataract codes are not covered through CPB 0393's framework.
Similarly, CPT 67107 (scleral buckling for retinal detachment repair) sits in the not-covered group here. Scleral buckling is a distinct procedure from vitrectomy. If your surgeon performs scleral buckling without vitrectomy, CPB 0393 does not apply, and you need to route that claim through a different policy pathway.
The other ICD-10 to watch: H43.391–H43.399 (other vitreous opacities) appears in the policy data with a notation that these codes are not covered for this indication. This distinguishes general vitreous opacities from the covered subset of vitreous membranes and strands (H43.311–H43.319). The distinction is narrow but real — code selection at this level directly determines whether a claim pays or denies.
Coverage Indications at a Glance
Note: The CPT codes listed below reflect clinical guidance based on code descriptions. CPB 0393 lists CPT 67036–67043 as a group covered when criteria are met — it does not assign specific CPT codes to specific indications.
| Indication | Status | Relevant ICD-10 Codes | Notes |
|---|---|---|---|
| Epiretinal membrane with progression/worsening vision | Covered | H35.371–H35.379 | Progression must be documented — stable ERM alone not sufficient |
| Macular hole repair | Covered | H35.341–H35.349 | ILM peeling typically bundled with 67042 |
| Proliferative retinopathy (including diabetic) | Covered | E10.311–E10.39, E11.311–E11.39 | Panretinal photocoagulation add-on (67040) eligible per code description |
| Rapidly progressing infectious endophthalmitis | Covered | H44.1–H44.2 | "Rapidly progressing" qualifier — document timeline in notes |
| Removal of silicone oil (retinal detachment treatment) | Covered | — | Prior silicone oil placement must be documented in chart |
| Retinal detachments secondary to vitreous strands | Covered | H33.1–H33.8 | Complex detachments may require 67113 per code description |
| RPE65 mutation-associated retinal dystrophy | Covered | H35.50 | Luxturna administration billed under CPB 0927 separately |
| Traumatic penetrating ocular injury | Covered | — | Confirm ICD-10 specificity for injury mechanism |
| Vitreous loss incident to cataract surgery | Covered | H43.89–H43.9 | Intraoperative complication — document clearly |
| Vitreoretinal lymphoma | Covered | C69.20–C69.22, C85.11, C85.91 | Verify prior authorization directly with Aetna |
| Vitreous membranes, strands, opacities (hemorrhage/other) | Covered | H43.311–H43.319, H43.10–H43.13 | H43.391–H43.399 (other opacities) are NOT covered |
| Vitreous retraction | Covered | H43.89–H43.9 | Document retraction vs. other vitreous pathology |
| Post-vitrectomy face support device | Covered | [DME code — confirm with supplier] | Patient must be post-vitrectomy and require face-down positioning |
| Cataract extraction codes (66850, 66852, 66982, 66984, 66987–66991) | Not Covered under CPB 0393 | — | Route through separate cataract policy pathway |
| Scleral buckling — CPT 67107 | Not Covered under CPB 0393 | — | Vitrectomy must be performed; pure buckling excluded |
| General vitreous opacities — H43.391–H43.399 | Not Covered | — | Covered subset is H43.311–H43.319 only |
Aetna Vitrectomy Billing Guidelines and Action Items 2025
The effective date is September 26, 2025. If your practice has not yet reviewed active Aetna claims and pending authorizations against the updated CPB 0393 criteria, do it this week.
| # | Action Item |
|---|---|
| 1 | Audit your charge capture for the epiretinal membrane qualifier. Claims for CPT 67041 (removal of preretinal cellular membrane) must include documentation of progression or vision worsening — not just a diagnosis of H35.371–H35.379. Pull any recent Aetna claims for this code and confirm the operative note and pre-authorization record reflect deterioration, not stable disease. |
| 2 | Separate your cataract and vitrectomy claims carefully. When both procedures occur in the same operative session, the cataract codes (66982, 66984, 66987–66991) are not covered under CPB 0393. Vitrectomy billing for that session should use CPT 67036 and any applicable add-on codes (67039, 67040), with the cataract claim routed through Aetna's lens extraction policy framework. Billing both under CPB 0393 is a claim denial waiting to happen. |
| 3 | Stop using H43.391–H43.399 for vitrectomy claims. These "other vitreous opacities" codes are explicitly excluded. If your documentation describes vitreous hemorrhage or strands, the correct ICD-10 range is H43.10–H43.13 for hemorrhage, or H43.311–H43.319 for membranes and strands. Run a query on Aetna claims in the past 90 days using H43.391–H43.399 paired with CPT 67036 and review for potential appeals. |
| 4 | Add face support device coverage to post-op workflows. If your surgeons routinely require face-down positioning after vitrectomy, the face support device is now explicitly covered. Work with your DME supplier to determine the appropriate billing code. The policy requires documentation that the patient underwent vitrectomy and that face-down positioning was required post-operatively. This is a recoverable revenue stream that many practices miss. |
| 5 | Flag vitreoretinal lymphoma and RPE65 cases for compliance review before surgery. These are low-volume indications with high clinical complexity. Both are covered under CPB 0393. Verify prior authorization requirements directly with Aetna before scheduling these procedures. If you're unsure how your specific patient mix intersects with these criteria, talk to your compliance officer before the September 26, 2025 effective date applies to active cases. |
| 6 | Update your encounter form or EHR order sets to reflect the 12-indication list. If your retinal surgery templates auto-populate diagnosis codes, make sure they map to the covered ICD-10 ranges in this policy. An outdated template that populates H43.391 instead of H43.311 will generate denials silently until someone audits the pattern. |
| Previous Version | Current Version |
|---|---|
| Coverage is considered experimental and investigational for all indications | Coverage is considered medically necessary when specific criteria are met |
| Prior authorization is not required | Prior authorization is required for initial treatment |
| Documentation must include clinical history | Documentation must include clinical history |
| Re-review every 24 months | Re-review every 12 months with updated clinical documentation |
CPT, HCPCS, and ICD-10 Codes for Vitrectomy Under CPB 0393
Covered CPT Codes (When Selection Criteria Are Met)
| Code | Type | Description |
|---|---|---|
| 67036 | CPT | Vitrectomy, mechanical, pars plana approach |
| 67039 | CPT | Vitrectomy with focal endolaser photocoagulation |
| 67040 | CPT | Vitrectomy with endolaser panretinal photocoagulation |
| 67041 | CPT | Vitrectomy with removal of preretinal cellular membrane (e.g., macular pucker) |
| 67042 | CPT | Vitrectomy with removal of internal limiting membrane of retina (e.g., macular hole repair, diabetic macular edema) |
| 67043 | CPT | Vitrectomy with removal of subretinal membrane (e.g., choroidal neovascularization) |
Not Covered Under CPB 0393
| Code | Type | Description | Reason |
|---|---|---|---|
| 66850 | CPT | Removal of lens material; phacofragmentation technique | Not covered for indications listed in CPB 0393 |
| 66852 | CPT | Removal of lens material; pars plana approach, with or without vitrectomy | Not covered for indications listed in CPB 0393 |
| 66982 | CPT | Extracapsular cataract removal with IOL insertion, complex | Not covered for indications listed in CPB 0393 |
| 66984 | CPT | Extracapsular cataract removal with IOL insertion, without endoscopic cyclophotocoagulation | Not covered for indications listed in CPB 0393 |
| 66987 | CPT | Extracapsular cataract removal with IOL insertion, complex, with endoscopic cyclophotocoagulation | Not covered for indications listed in CPB 0393 |
| 66988 | CPT | Extracapsular cataract removal with IOL insertion, with endoscopic cyclophotocoagulation | Not covered for indications listed in CPB 0393 |
| 66989 | CPT | Extracapsular cataract removal with IOL insertion, complex, with intraoperative OCT | Not covered for indications listed in CPB 0393 |
| 66991 | CPT | Extracapsular cataract removal with IOL insertion, with intraoperative OCT | Not covered for indications listed in CPB 0393 |
| 67107 | CPT | Repair of retinal detachment; scleral buckling | Not covered for indications listed in CPB 0393 |
Key ICD-10-CM Diagnosis Codes
| Code | Description |
|---|---|
| C69.20 | Malignant neoplasm of retina, unspecified eye |
| C69.21 | Malignant neoplasm of retina, right eye |
| C69.22 | Malignant neoplasm of retina, left eye |
| C85.11 | Unspecified B-cell lymphoma, lymph nodes of head, face, and neck |
| C85.91 | Non-Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck |
| E10.311–E10.39 | Type 1 diabetes mellitus with ophthalmic complications |
| E11.311–E11.39 | Type 2 diabetes mellitus with ophthalmic complications |
| H33.1–H33.8 | Retinal detachments and breaks |
| H35.341–H35.349 | Macular cyst, hole, or pseudohole |
| H35.371–H35.379 | Puckering of macula (epiretinal membrane with progression or worsening of vision) |
| H35.50 | Unspecified hereditary retinal dystrophy (RPE65 mutation-associated retinal dystrophy) |
| H35.89 | Other specified retinal disorders (acute retinal necrosis) |
| H43.10–H43.13 | Vitreous hemorrhage |
| H43.311–H43.319 | Vitreous membranes and strands |
| H43.391–H43.399 | Other vitreous opacities — NOT covered for vitrectomy indications |
| H43.89–H43.9 | Other and unspecified disorders of vitreous body (vitreous retraction; vitreous loss incident to cataract surgery) |
| H44.1–H44.2 | Purulent endophthalmitis |
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