TL;DR: Aetna, a CVS Health company, modified CPB 0228 covering cardiac CT, coronary CT angiography (CCTA), calcium scoring, and CT fractional flow reserve, effective February 27, 2026. If your team bills CPT 75574, 75571, 75572, 75573, or 75580 for Aetna members, read this before submitting your next claim.
This update to the Aetna cardiac CT coverage policy touches 71 CPT codes, one HCPCS code, and over 120 ICD-10-CM diagnosis codes. The policy also adds explicit guidance on newer technology codes—including 0623T through 0626T for coronary plaque analysis and CT-FFR, and 0992T/0993T, which Aetna now explicitly excludes. Cardiac imaging billing teams have real exposure here, especially anyone billing the newer Category III codes without checking CPB 0228 Aetna first.
Quick-Reference Table
| Field | Detail |
|---|---|
| Payer | Aetna, a CVS Health company |
| Policy | Cardiac Computed Tomography (CT), Coronary CT Angiography, Calcium Scoring and CT Fractional Flow Reserve |
| Policy Code | CPB 0228 |
| Change Type | Modified |
| Effective Date | February 27, 2026 |
| Impact Level | High |
| Specialties Affected | Cardiology, Radiology, Cardiac Surgery, Electrophysiology, Cardiovascular Imaging |
| Key Action | Audit charge capture for Category III codes 0992T and 0993T — Aetna now explicitly excludes both |
Aetna Cardiac CT and CCTA Coverage Criteria and Medical Necessity Requirements 2026
The real issue with CPB 0228 is precision. Aetna's cardiac CT coverage policy doesn't just ask whether your patient has chest pain. It asks what their pre-test probability is, how you calculated it, and whether you used Framingham risk scoring, Pooled Cohort Equations, or ACC criteria. Getting the medical necessity documentation wrong on these claims is a fast path to a claim denial.
CCTA of the Coronary Arteries (CPT 75574)
Aetna covers CCTA using 64-slice or greater for nine distinct indications. Each has its own documentation requirements. The broadest category covers ruling out obstructive coronary stenosis in symptomatic patients with low or intermediate pre-test probability of coronary artery disease or atherosclerotic cardiovascular disease. Your documentation must reference one of three accepted risk stratification tools: Framingham, Pooled Cohort Equations, or ACC criteria.
A second covered indication: patients with a positive stress test (≥1 mm ST segment depression) who also have a low or intermediate pre-test probability by the same risk tools. Don't assume the positive stress test alone gets you there — Aetna wants the pre-test probability documented too.
Asymptomatic patients are covered only at intermediate pre-test probability, and only when the stress test is equivocal, uninterpretable, or when resting ECG changes (LBBB, pathologic Q-waves, RBBB with LAFB) suggest CAD as a possible cause. Aetna includes a pointed note here: the American Heart Association recommends against routine stress testing for asymptomatic adults. That note is in the policy for a reason — Aetna is flagging that they'll scrutinize these claims.
Preoperative and Procedural Indications
Aetna covers CCTA for preoperative assessment before high-risk non-cardiac surgery when an imaging stress test or invasive coronary angiography is being deferred. The ACC defines high-risk surgery as emergent operations (especially in the elderly), aortic and major vascular surgeries, peripheral vascular surgeries, and prolonged abdominal or thoracic procedures with significant fluid shifts or blood loss.
For planned non-coronary cardiac surgery — valve repair, congenital heart disease correction, pericardial disease — CCTA is covered as an alternative to cardiac catheterization as the initial imaging study, but only in patients with low or intermediate pretest risk of obstructive CAD.
CCTA before transcatheter aortic valve replacement (TAVR) — billed under CPT codes 33361 through 33369 — is explicitly covered for aortic valve annulus assessment.
CT Fractional Flow Reserve (CPT 75580 and 0626T)
CT-FFR coverage requires a prior CCTA showing coronary artery disease of uncertain functional significance, or a non-diagnostic CCTA. You can't bill 75580 or 0626T as a standalone without that preceding CCTA result. Document the prior study clearly in the record and on the claim.
Calcium Scoring (CPT 75571) and HCPCS S8092
Calcium scoring is covered for asymptomatic patients when specific risk criteria are met. HCPCS S8092 — covering electron beam CT (ultrafast CT, cine CT) — is listed as covered when policy indications are met. This is worth noting because S8092 doesn't show up on every team's radar for prior authorization workflows.
Pulmonary Vein Mapping
CCTA for cardiac morphology and pulmonary vein mapping (CPT 75572, 75573) is covered for two specific indications: biventricular pacemaker patients needing coronary vein mapping for lead placement, and patients undergoing pulmonary vein isolation for atrial fibrillation (both pre- and post-ablation). If your electrophysiology program bills these, make sure the indication language in your documentation matches one of those two exactly.
Coronary Anomalies in Young Patients
Detection and delineation of suspected coronary anomalies is covered in patients under 40 with suggestive symptoms. The policy lists specific symptoms by age group. For adults and children: angina, syncope, arrhythmia, and exertional dyspnea without another known cause. For infants: dyspnea, tachypnea, wheezing, pallor, irritability (episodic crying), diaphoresis, poor feeding, and failure to thrive. If you're billing this indication for a pediatric patient, your documentation needs to match one of these clinical pictures.
Aetna Cardiac CT Exclusions and Non-Covered Indications
Aetna's CPB 0228 explicitly excludes four Category III codes. These are not gray areas — they're listed under "CPT codes not covered for indications listed in the CPB."
0992T and 0993T — Perivascular Fat Analysis
These two codes cover noninvasive cardiac risk assessment derived from software analysis of perivascular fat attenuation using CT data. Aetna does not cover either code. If your radiology group or cardiology practice recently added these to your charge capture, remove them from Aetna claims now.
0721T and 0722T — Quantitative CT Tissue Characterization
These codes cover quantitative CT tissue characterization, including interpretation and report. Aetna also excludes both. These are distinct from the covered plaque analysis codes (0623T–0626T), so don't mix them up in your billing.
The line between covered plaque analysis (0623T–0626T, the Cleerly Coronary Report pathway) and excluded tissue characterization (0721T, 0722T) is genuinely narrow. If your team is billing any of these, loop in your compliance officer before the February 27, 2026 effective date to confirm you're on the right side of that line.
Coverage Indications at a Glance
| Indication | Status | Relevant Codes | Notes |
|---|---|---|---|
| Rule out obstructive CAD — symptomatic, low/intermediate pre-test probability | Covered | 75574 | Requires Framingham, PCE, or ACC risk stratification documentation |
| Positive stress test (≥1mm ST depression), low/intermediate pre-test probability | Covered | 75574 | Pre-test probability must still be documented |
| Asymptomatic, intermediate pre-test probability, equivocal/uninterpretable stress test or resting ECG changes | Covered | 75574 | AHA advises against routine stress testing in asymptomatic adults — expect scrutiny |
| Pre-op assessment, high-risk non-cardiac surgery | Covered | 75574 | Surgery must meet ACC high-risk definition |
| Pre-op for non-coronary cardiac surgery (valve, congenital, pericardial) | Covered | 75574 | Low/intermediate CAD pretest risk required; replaces initial cath |
| Coronary anomaly detection in patients under 40 with suggestive symptoms | Covered | 75574 | Age and symptom criteria must be met; documentation must match listed symptoms |
| In-stent stenosis evaluation | Covered | 75574 | — |
| CT-FFR calculation after non-diagnostic or uncertain CCTA | Covered | 75580, 0626T | Prior CCTA required; must show CAD of uncertain significance |
| Coronary ectasia evaluation | Covered | 75574 | — |
| Pulmonary vein mapping — biventricular pacemaker lead placement | Covered | 75572, 75573 | — |
| Pulmonary vein mapping — pre/post atrial fibrillation ablation | Covered | 75572, 75573 | — |
| TAVR preoperative aortic valve annulus assessment | Covered | 75574 | Related procedure codes: 33361–33369 |
| Calcium scoring — asymptomatic patients meeting criteria | Covered | 75571, S8092 | Risk criteria must be documented |
| Coronary atherosclerotic plaque analysis (Cleerly pathway) | Covered (criteria apply) | 0623T, 0624T, 0625T | All three codes in the series should be billed together |
| Intraprocedural CT-FFR with 3D mapping | Covered (criteria apply) | 0626T | — |
| Noninvasive arterial plaque analysis — non-coronary vessels | Covered (criteria apply) | 0710T, 0711T, 0712T, 0713T | — |
| Quantitative CT tissue characterization (0721T, 0722T) | Not Covered | 0721T, 0722T | Explicitly excluded by CPB 0228 |
| Perivascular fat attenuation analysis for cardiac risk (0992T, 0993T) | Not Covered | 0992T, 0993T | Explicitly excluded by CPB 0228 |
Aetna Cardiac CT Billing Guidelines and Action Items 2026
| # | Action Item |
|---|---|
| 1 | Pull every claim with 0992T or 0993T before February 27, 2026. Aetna now explicitly excludes both codes. Any claim submitted on or after the effective date will deny based on Aetna's explicit exclusion of these codes under CPB 0228. |
| 2 | Audit your 0721T and 0722T charge capture. These quantitative CT tissue characterization codes are also excluded. They're easy to confuse with the covered plaque analysis codes (0623T–0625T). Run a code-level audit across your Aetna CCTA claims to confirm you're not billing them. |
| 3 | Update your medical necessity documentation templates for 75574. Every CCTA claim needs documented pre-test probability using Framingham, Pooled Cohort Equations, or ACC criteria. If your intake templates don't capture this automatically, fix that before the effective date of February 27, 2026. |
| 4 | Build a prior authorization check for 75580 and 0626T. CT-FFR reimbursement from Aetna depends on a documented prior CCTA showing CAD of uncertain functional significance or a non-diagnostic result. Make sure your prior auth workflow captures the preceding CCTA before you schedule the FFR study. |
| 5 | Check HCPCS S8092 against your prior authorization workflow. If your facility uses electron beam CT and bills S8092, confirm it's in your prior auth lookup list for Aetna. It's covered, but that coverage depends on meeting the same selection criteria as the rest of CPB 0228. |
| 6 | Review pediatric CCTA billing for coronary anomaly indications. Aetna's symptom list for patients under 40 is specific. Your documentation for these cases — especially infants — should reflect the exact clinical presentations listed in CPB 0228. Vague "chest pain" documentation won't hold up on review. |
| 7 | Confirm your 0623T–0625T billing sequence. These three codes cover the Cleerly Coronary Report pathway: automated quantification (0623T), data preparation and transmission (0624T), and physician review and interpretation (0625T). They function as a series. Bill them together with consistent documentation. |
| Previous Version | Current Version |
|---|---|
| Coverage is considered experimental and investigational for all indications | Coverage is considered medically necessary when specific criteria are met |
| Prior authorization is not required | Prior authorization is required for initial treatment |
| Documentation must include clinical history | Documentation must include clinical history |
| Re-review every 24 months | Re-review every 12 months with updated clinical documentation |
CPT, HCPCS, and ICD-10 Codes for Cardiac CT Under CPB 0228
Covered CPT Codes (When Selection Criteria Are Met)
| Code | Type | Description |
|---|---|---|
| 0623T | CPT | Automated quantification and characterization of coronary atherosclerotic plaque to assess severity (Cleerly Coronary Report) |
| 0624T | CPT | Data preparation and transmission (Cleerly Coronary Report) |
| 0625T | CPT | Review of computerized analysis output to reconcile discordant data, interpretation and report (Cleerly Coronary Report) |
| 0626T | CPT | Intraprocedural coronary fractional flow reserve (FFR) with 3D functional mapping of color-coded FFR values |
| 0710T | CPT | Noninvasive arterial plaque analysis using software processing of data from non-coronary computerized tomography angiography |
| 0711T | CPT | Data preparation and transmission (non-coronary plaque analysis) |
| 0712T | CPT | Quantification of the structure and composition of the vessel wall and assessment for lipid-rich necrotic core |
| 0713T | CPT | Data review, interpretation and report (non-coronary plaque analysis) |
| 70471 | CPT | Computed tomographic angiography (CTA), head and neck, with contrast material(s), including noncontrast images |
| 75571 | CPT | Computed tomography, heart, without contrast material, with quantitative evaluation of coronary calcium |
| 75572 | CPT | Computed tomography, heart, with contrast material, for evaluation of cardiac structure and morphology |
| 75573 | CPT | Computed tomography, heart, with contrast material, for evaluation of cardiac structure and morphology (congenital heart disease) |
| 75574 | CPT | Computed tomographic angiography, heart, coronary arteries and bypass grafts (when present), with contrast material(s) |
| 75580 | CPT | Noninvasive estimate of coronary fractional flow reserve (FFR) derived from augmentative software analysis of CCTA data |
Not Covered / Experimental Codes
| Code | Type | Description | Reason |
|---|---|---|---|
| 0721T | CPT | Quantitative CT tissue characterization, including interpretation and report | Not covered for indications listed in CPB 0228 |
| 0722T | CPT | Quantitative CT tissue characterization, including interpretation and report (add-on) | Not covered for indications listed in CPB 0228 |
| 0992T | CPT | Noninvasive assessment of cardiac risk derived from augmentative software analysis of perivascular fat attenuation using CT data | Not covered for indications listed in CPB 0228 |
| 0993T | CPT | Noninvasive assessment of cardiac risk derived from augmentative software analysis of perivascular fat attenuation using CT data (add-on) | Not covered for indications listed in CPB 0228 |
Covered HCPCS Codes
| Code | Type | Description |
|---|---|---|
| S8092 | HCPCS | Electron beam computed tomography (ultrafast CT, cine CT) |
Key ICD-10-CM Diagnosis Codes
| Code | Description |
|---|---|
| C38.0 | Malignant neoplasm of heart (atrial angiosarcoma) |
| E08.00–E09.9 | Diabetes mellitus due to underlying condition (asymptomatic persons age 40 and older) |
| E08.59 | Diabetes mellitus due to underlying condition with other circulatory complications (coronary atherosclerosis) |
| E09.59 | Drug or chemical induced diabetes mellitus with other circulatory complications (coronary atherosclerosis) |
| E10.10–E13.9 | Diabetes mellitus (asymptomatic persons age 40 and older) |
| E10.59 | Type 1 diabetes mellitus with other circulatory complications (coronary atherosclerosis in symptomatic patients) |
| E11.59 | Type 2 diabetes mellitus with other circulatory complications (coronary atherosclerosis in symptomatic patients) |
| E13.59 | Other specified diabetes mellitus with other circulatory complications (coronary atherosclerosis in symptomatic patients) |
The full ICD-10-CM list for CPB 0228 includes 120+ codes. Review the complete list at Aetna CPB 0228 before building your payer-specific billing guidelines.
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