TL;DR: Aetna, a CVS Health company, modified CPB 0188 covering total body photography and dermoscopy, effective December 18, 2025. Here's what your billing team needs to act on now.
Aetna's updated dermoscopy and total body photography coverage policy tightens the line between covered services and technologies it considers experimental. The policy governs CPT 96904 as the primary covered code and places a long list of newer diagnostic tools — including CPT codes 96931–96936 (reflectance confocal microscopy), 0658T (electrical impedance spectroscopy), 0700T–0701T (molecular fluorescent imaging), and 0089U (DermTech gene expression) — firmly in the "not covered" column. If your dermatology billing team uses any of these codes for Aetna members, this update is a direct denial risk.
Quick-Reference Table
| Field | Detail |
|---|---|
| Payer | Aetna, a CVS Health company |
| Policy | Total Body Photography, Dermoscopy and Other Selected Noninvasive Dermatologic Tests |
| Policy Code | CPB 0188 |
| Change Type | Modified |
| Effective Date | December 18, 2025 |
| Impact Level | High |
| Specialties Affected | Dermatology, Plastic Surgery, Oncology (Cutaneous) |
| Key Action | Audit any claims billing experimental codes (0089U, 0658T, 96931–96936, 0700T–0701T) for Aetna members and stop submitting them without an appeal strategy in place |
Aetna Total Body Photography and Dermoscopy Coverage Criteria and Medical Necessity Requirements 2025
CPB 0188 Aetna's coverage policy draws a clear box around what qualifies for reimbursement. Aetna covers total body photography (TBP) and dermoscopy — also called epiluminescence microscopy (ELM), digital epiluminescence microscopy (DELM), dermatoscopy, skin videomicroscopy, or in-vivo cutaneous surface microscopy — only when documented medical necessity exists.
Medical necessity applies when a member has a personal history or close family history of at least one of the following:
| # | Covered Indication |
|---|---|
| 1 | Atypical nevi |
| 2 | Dysplastic nevi |
| 3 | Melanoma |
| 4 | Non-melanoma skin cancers |
A member doesn't need a personal diagnosis — a close family history of any of the covered conditions can also qualify. Document that family history explicitly in the medical record. This is a common miss that triggers claim denial.
The repeat study rule is just as important. Aetna does not consider repeat TBP or dermoscopy medically necessary more often than every 24 months. Bill CPT 96904 more frequently than that without a strong medical justification and you'll get denied. Document the clinical reasoning explicitly if your dermatologist believes a shorter interval is warranted — don't assume the claim will pass without it.
Dermoscopy billing under this policy hinges on the indication. The covered indications above are narrow. Aetna doesn't extend this coverage policy broadly — any indication outside those four categories falls into experimental territory.
Prior authorization requirements are not explicitly detailed in CPB 0188's criteria section, but given Aetna's history with specialty imaging services, verify prior auth requirements for CPT 96904 through Aetna's portal before scheduling. Assuming no prior auth is required for a "simple" dermoscopy visit is how reimbursement problems start.
Aetna Dermoscopy and TBP Exclusions and Non-Covered Indications
This is the section that carries the most financial exposure. Aetna's list of experimental, investigational, or unproven services under CPB 0188 is long — and it covers technologies that some practices are actively using and billing.
Computerized TBP systems are not covered. Aetna explicitly calls out MelaFind, MoleMapCD, and MoleMate. These systems have not shown better health outcomes than conventional TBP, per Aetna's assessment. If your practice uses a computerized TBP platform and bills it for Aetna members, you are billing into a wall.
Dermoscopy for the following indications is also not covered:
| # | Excluded Procedure |
|---|---|
| 1 | Assessment of vulvar intraepithelial neoplasia |
| 2 | Delineation of basal cell carcinoma for Mohs micrographic surgery (CPT 17311–17315 are listed as related codes, but dermoscopy for BCC delineation pre-Mohs is excluded) |
| 3 | Evaluation of non-parasitic skin infections |
That Mohs exclusion is worth flagging. Some practices use dermoscopy to help delineate BCC margins before Mohs. Aetna will not cover dermoscopy for this purpose. Keep those services separate in documentation and billing.
The experimental list for evaluating dysplastic and atypical nevi is extensive. Aetna considers the following technologies unproven for early melanoma detection:
| # | Excluded Procedure |
|---|---|
| 1 | Confocal scanning laser microscopy |
| 2 | DermTech Nevome and DermTech Pigmented Lesion Assay (PLA) — CPT 0089U |
| 3 | Electrical impedance devices — CPT 0658T |
| 4 | High-resolution ultrasonography |
| 5 | Multi-photon laser scanning microscopy |
| 6 | Multi-spectral image analysis |
| 7 | Non-invasive gene expression "patch biopsy" |
| 8 | Optical coherence tomography — CPT 0470T and 0471T |
| 9 | Reflectance confocal microscopy (RCM) — CPT 96931, 96932, 96933, 96934, 96935, 96936 |
| 10 | Spectroscopy (electrical impedance and optical, including DermaSensor) — CPT 1020T |
| 11 | Teledermatology and teledermoscopy |
| 12 | Visual image analysis |
| 13 | Molecular fluorescent imaging (Orlucent system) — CPT 0700T, 0701T |
| 14 | mRNA skin-surface patch testing (Mind.Px) — CPT 0258U |
| 15 | AURA (Vita Imaging) |
The RCM codes alone represent significant reimbursement exposure. CPT 96931–96936 describe reflectance confocal microscopy for cellular and sub-cellular skin imaging. These codes have been growing in use in advanced dermatology practices. Aetna is not paying for them under this coverage policy.
The DermTech PLA (0089U) exclusion is also notable. This non-invasive gene expression patch test has been marketed as a way to reduce unnecessary biopsies. Aetna's position is that its predictive clinical value hasn't been established. Don't bill it expecting payment from Aetna members.
Coverage Indications at a Glance
| Indication | Status | Relevant Codes | Notes |
|---|---|---|---|
| TBP/Dermoscopy — personal or family history of atypical nevi | Covered | CPT 96904 | Repeat no more than every 24 months |
| TBP/Dermoscopy — personal or family history of dysplastic nevi | Covered | CPT 96904 | Repeat no more than every 24 months |
| TBP/Dermoscopy — personal or family history of melanoma | Covered | CPT 96904 | Document family history explicitly |
| TBP/Dermoscopy — personal or family history of non-melanoma skin cancer | Covered | CPT 96904 | Includes BCC and SCC history |
| Computerized TBP (MelaFind, MoleMapCD, MoleMate) | Experimental | — | Not covered; no superior outcomes vs. conventional TBP |
| Dermoscopy for vulvar intraepithelial neoplasia | Experimental | — | Not covered |
| Dermoscopy for BCC delineation (pre-Mohs) | Experimental | CPT 17311–17315 (related) | Dermoscopy for this purpose not covered |
| Dermoscopy for non-parasitic skin infections | Experimental | — | Not covered |
| Reflectance confocal microscopy (RCM) | Experimental | CPT 96931–96936 | Not covered for melanoma risk evaluation |
| Optical coherence tomography (OCT) | Experimental | CPT 0470T, 0471T | Not covered |
| Electrical impedance spectroscopy | Experimental | CPT 0658T | Not covered |
| Gene expression profiling — DermTech PLA / Nevome | Experimental | CPT 0089U | Predictive value not established |
| Molecular fluorescent imaging (Orlucent) | Experimental | CPT 0700T, 0701T | Lack of evidence of effectiveness |
| mRNA patch testing for psoriasis biologic selection (Mind.Px) | Experimental | CPT 0258U | Not covered |
| Raman spectroscopy | Experimental | CPT 1020T | Not covered |
| Teledermatology / teledermoscopy | Experimental | — | Not covered under this policy |
| AURA (Vita Imaging) | Experimental | — | Not covered |
Aetna Dermoscopy Billing Guidelines and Action Items 2025
| # | Action Item |
|---|---|
| 1 | Audit your Aetna claims for CPT 96931–96936 now. RCM codes are a high-denial risk under this policy. Pull any open or pending Aetna claims using these codes before December 18, 2025, and either appeal with strong clinical justification or write them off. Don't let them age into timely filing issues. |
| 2 | Stop billing 0089U for Aetna members without a plan. DermTech PLA (CPT 0089U) is explicitly excluded. If your practice runs this test and bills it, you're absorbing the cost or billing the patient — neither of which happens cleanly without a written financial responsibility notice in place. Make sure patients are notified before the test that Aetna will not cover it. Note: ABNs are a Medicare instrument. For commercial plans like Aetna, use a financial liability notice appropriate to your plan contract. |
| 3 | Verify diagnosis code documentation for every CPT 96904 claim. The covered indications require documented personal or close family history of atypical nevi, dysplastic nevi, melanoma, or non-melanoma skin cancer. Use the correct ICD-10 codes from the C43 and C44 series (melanoma and BCC respectively) paired with personal/family history codes. Missing or mismatched diagnosis codes are the fastest route to a claim denial. |
| 4 | Flag the 24-month repeat rule in your scheduling system. Build a check into your EHR or practice management system so your scheduling team knows when the last TBP or dermoscopy was billed for each Aetna member. Repeat studies billed inside 24 months need documented clinical justification — not just a routine follow-up note. |
| 5 | Separate dermoscopy documentation from Mohs pre-op workup. If your dermatologist performs dermoscopy before Mohs surgery for BCC, don't bill it as part of the Mohs episode for Aetna. Aetna excludes dermoscopy for BCC delineation. The Mohs codes (CPT 17311–17315) are listed as related codes, but that dermoscopy component won't get paid. Document and bill Mohs separately and do not bundle dermoscopy charges into that encounter. |
| 6 | Check prior authorization requirements before December 18, 2025. Confirm Aetna's current prior auth requirements for CPT 96904 in your plan contracts. Coverage policy changes sometimes trigger updates to prior auth lists. Don't find out after the fact. |
| 7 | Issue written financial responsibility notices for experimental services. For any technology on Aetna's experimental list — RCM, OCT, gene expression patches, molecular fluorescent imaging — provide patients with written notice that Aetna considers the service unproven and won't cover it. This protects your practice from billing disputes and gives patients the chance to consent and pay out of pocket. Note: ABNs are a Medicare instrument. For commercial plans like Aetna, use a financial liability notice appropriate to your plan contract. |
| Previous Version | Current Version |
|---|---|
| Coverage is considered experimental and investigational for all indications | Coverage is considered medically necessary when specific criteria are met |
| Prior authorization is not required | Prior authorization is required for initial treatment |
| Documentation must include clinical history | Documentation must include clinical history |
| Re-review every 24 months | Re-review every 12 months with updated clinical documentation |
CPT, HCPCS, and ICD-10 Codes for Dermoscopy and Total Body Photography Under CPB 0188
Covered CPT Codes (When Selection Criteria Are Met)
| Code | Type | Description |
|---|---|---|
| 96904 | CPT | Whole body integumentary photography, for monitoring of high-risk patients with dysplastic nevus syndrome |
Not Covered / Experimental CPT Codes
| Code | Type | Description | Reason |
|---|---|---|---|
| 0089U | CPT | Oncology (melanoma), gene expression profiling by RTqPCR, PRAME and LINC00518, superficial collection | Experimental — DermTech PLA; predictive clinical value not established |
| 0258U | CPT | Autoimmune (psoriasis), mRNA, next-generation sequencing, gene expression profiling of 50–100 genes | Experimental — Mind.Px mRNA patch; psoriasis biologic selection value not established |
| 0470T | CPT | Optical coherence tomography (OCT) for microstructural and morphological imaging of skin, image acquisition | Experimental — OCT; clinical value not established |
| 0471T | CPT | OCT, each additional lesion (add-on) | Experimental — OCT add-on |
| 0658T | CPT | Electrical impedance spectroscopy of 1 or more skin lesions for automated melanoma risk score | Experimental — electrical impedance device |
| 0700T | CPT | Molecular fluorescent imaging of suspicious nevus; first lesion | Experimental — Orlucent system; lack of evidence of effectiveness |
| 0701T | CPT | Molecular fluorescent imaging, each additional lesion (add-on) | Experimental — Orlucent add-on |
| 1020T | CPT | Raman spectroscopy of 1 or more skin lesions, with probability score for malignant risk | Experimental — spectroscopy |
| 96931 | CPT | Reflectance confocal microscopy (RCM) for cellular and sub-cellular imaging of skin | Experimental — RCM |
| 96932 | CPT | Reflectance confocal microscopy (RCM) for cellular and sub-cellular imaging of skin | Experimental — RCM |
| 96933 | CPT | Reflectance confocal microscopy (RCM) for cellular and sub-cellular imaging of skin | Experimental — RCM |
| 96934 | CPT | Reflectance confocal microscopy (RCM) for cellular and sub-cellular imaging of skin | Experimental — RCM |
| 96935 | CPT | Reflectance confocal microscopy (RCM) for cellular and sub-cellular imaging of skin | Experimental — RCM |
| 96936 | CPT | Reflectance confocal microscopy (RCM) for cellular and sub-cellular imaging of skin | Experimental — RCM |
Key ICD-10-CM Diagnosis Codes
| Code | Description |
|---|---|
| C43.0 | Malignant melanoma of lip |
| C43.1 | Malignant melanoma of eyelid |
| C43.2 | Malignant melanoma of ear and external auricular canal |
| C43.3 | Malignant melanoma of other and unspecified parts of face |
| C43.4 | Malignant melanoma of scalp and neck |
| C43.5 | Malignant melanoma of trunk |
| C43.6 | Malignant melanoma of upper limb |
| C43.7 | Malignant melanoma of lower limb |
| C43.8 | Malignant melanoma, overlapping sites |
| C43.9 | Malignant melanoma of skin, unspecified |
| C44.01 | Basal cell carcinoma of skin of lip |
| C44.111–C44.1192 | Basal cell carcinoma of skin of eyelid (range) |
| C44.211–C44.219 | Basal cell carcinoma of skin of ear and external auricular canal |
| C44.310–C44.319 | Basal cell carcinoma of skin of other and unspecified parts of face |
| C44.41 | Basal cell carcinoma of skin of scalp and neck |
| C44.510–C44.519 | Basal cell carcinoma of skin of trunk |
| C44.611–C44.619 | Basal cell carcinoma of skin of upper limb |
| C44.711–C44.718 | Basal cell carcinoma of skin of lower limb |
Note: The full policy lists 81 ICD-10-CM codes. Review the complete list at CPB 0188 on Aetna's site to confirm applicable diagnosis codes for your patient mix.
If your practice offers advanced dermatologic imaging — RCM, OCT, gene expression testing — and you have a significant Aetna patient population, talk to your compliance officer before the December 18, 2025 effective date. The experimental list in CPB 0188 is broad. Some of these exclusions will surprise practices that have been billing these codes without denial. Better to audit now than to unwind six months of denied claims in Q1 2026.
Get the Full Picture for CPT 96904
Track this policy across versions, search 1,500+ policies by CPT code, and get real-time alerts when any payer changes coverage.