TL;DR: Aetna, a CVS Health company, modified CPB 0188 covering total body photography and dermoscopy, effective December 18, 2025. Here's what your billing team needs to act on now.

Aetna's updated dermoscopy and total body photography coverage policy tightens the line between covered services and technologies it considers experimental. The policy governs CPT 96904 as the primary covered code and places a long list of newer diagnostic tools — including CPT codes 96931–96936 (reflectance confocal microscopy), 0658T (electrical impedance spectroscopy), 0700T–0701T (molecular fluorescent imaging), and 0089U (DermTech gene expression) — firmly in the "not covered" column. If your dermatology billing team uses any of these codes for Aetna members, this update is a direct denial risk.


Quick-Reference Table

Field Detail
Payer Aetna, a CVS Health company
Policy Total Body Photography, Dermoscopy and Other Selected Noninvasive Dermatologic Tests
Policy Code CPB 0188
Change Type Modified
Effective Date December 18, 2025
Impact Level High
Specialties Affected Dermatology, Plastic Surgery, Oncology (Cutaneous)
Key Action Audit any claims billing experimental codes (0089U, 0658T, 96931–96936, 0700T–0701T) for Aetna members and stop submitting them without an appeal strategy in place

Aetna Total Body Photography and Dermoscopy Coverage Criteria and Medical Necessity Requirements 2025

CPB 0188 Aetna's coverage policy draws a clear box around what qualifies for reimbursement. Aetna covers total body photography (TBP) and dermoscopy — also called epiluminescence microscopy (ELM), digital epiluminescence microscopy (DELM), dermatoscopy, skin videomicroscopy, or in-vivo cutaneous surface microscopy — only when documented medical necessity exists.

Medical necessity applies when a member has a personal history or close family history of at least one of the following:

#Covered Indication
1Atypical nevi
2Dysplastic nevi
3Melanoma
+ 1 more indications

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A member doesn't need a personal diagnosis — a close family history of any of the covered conditions can also qualify. Document that family history explicitly in the medical record. This is a common miss that triggers claim denial.

The repeat study rule is just as important. Aetna does not consider repeat TBP or dermoscopy medically necessary more often than every 24 months. Bill CPT 96904 more frequently than that without a strong medical justification and you'll get denied. Document the clinical reasoning explicitly if your dermatologist believes a shorter interval is warranted — don't assume the claim will pass without it.

Dermoscopy billing under this policy hinges on the indication. The covered indications above are narrow. Aetna doesn't extend this coverage policy broadly — any indication outside those four categories falls into experimental territory.

Prior authorization requirements are not explicitly detailed in CPB 0188's criteria section, but given Aetna's history with specialty imaging services, verify prior auth requirements for CPT 96904 through Aetna's portal before scheduling. Assuming no prior auth is required for a "simple" dermoscopy visit is how reimbursement problems start.


Aetna Dermoscopy and TBP Exclusions and Non-Covered Indications

This is the section that carries the most financial exposure. Aetna's list of experimental, investigational, or unproven services under CPB 0188 is long — and it covers technologies that some practices are actively using and billing.

Computerized TBP systems are not covered. Aetna explicitly calls out MelaFind, MoleMapCD, and MoleMate. These systems have not shown better health outcomes than conventional TBP, per Aetna's assessment. If your practice uses a computerized TBP platform and bills it for Aetna members, you are billing into a wall.

Dermoscopy for the following indications is also not covered:

#Excluded Procedure
1Assessment of vulvar intraepithelial neoplasia
2Delineation of basal cell carcinoma for Mohs micrographic surgery (CPT 17311–17315 are listed as related codes, but dermoscopy for BCC delineation pre-Mohs is excluded)
3Evaluation of non-parasitic skin infections

That Mohs exclusion is worth flagging. Some practices use dermoscopy to help delineate BCC margins before Mohs. Aetna will not cover dermoscopy for this purpose. Keep those services separate in documentation and billing.

The experimental list for evaluating dysplastic and atypical nevi is extensive. Aetna considers the following technologies unproven for early melanoma detection:

#Excluded Procedure
1Confocal scanning laser microscopy
2DermTech Nevome and DermTech Pigmented Lesion Assay (PLA) — CPT 0089U
3Electrical impedance devices — CPT 0658T
+ 12 more exclusions

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The RCM codes alone represent significant reimbursement exposure. CPT 96931–96936 describe reflectance confocal microscopy for cellular and sub-cellular skin imaging. These codes have been growing in use in advanced dermatology practices. Aetna is not paying for them under this coverage policy.

The DermTech PLA (0089U) exclusion is also notable. This non-invasive gene expression patch test has been marketed as a way to reduce unnecessary biopsies. Aetna's position is that its predictive clinical value hasn't been established. Don't bill it expecting payment from Aetna members.


Coverage Indications at a Glance

Indication Status Relevant Codes Notes
TBP/Dermoscopy — personal or family history of atypical nevi Covered CPT 96904 Repeat no more than every 24 months
TBP/Dermoscopy — personal or family history of dysplastic nevi Covered CPT 96904 Repeat no more than every 24 months
TBP/Dermoscopy — personal or family history of melanoma Covered CPT 96904 Document family history explicitly
+ 14 more indications

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This policy is now in effect (since 2025-12-18). Verify your claims match the updated criteria above.

Aetna Dermoscopy Billing Guidelines and Action Items 2025

#Action Item
1

Audit your Aetna claims for CPT 96931–96936 now. RCM codes are a high-denial risk under this policy. Pull any open or pending Aetna claims using these codes before December 18, 2025, and either appeal with strong clinical justification or write them off. Don't let them age into timely filing issues.

2

Stop billing 0089U for Aetna members without a plan. DermTech PLA (CPT 0089U) is explicitly excluded. If your practice runs this test and bills it, you're absorbing the cost or billing the patient — neither of which happens cleanly without a written financial responsibility notice in place. Make sure patients are notified before the test that Aetna will not cover it. Note: ABNs are a Medicare instrument. For commercial plans like Aetna, use a financial liability notice appropriate to your plan contract.

3

Verify diagnosis code documentation for every CPT 96904 claim. The covered indications require documented personal or close family history of atypical nevi, dysplastic nevi, melanoma, or non-melanoma skin cancer. Use the correct ICD-10 codes from the C43 and C44 series (melanoma and BCC respectively) paired with personal/family history codes. Missing or mismatched diagnosis codes are the fastest route to a claim denial.

+ 4 more action items

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Sample Version Diff Line-by-line changes
Previous VersionCurrent Version
Coverage is considered experimental and investigational for all indicationsCoverage is considered medically necessary when specific criteria are met
Prior authorization is not requiredPrior authorization is required for initial treatment
Documentation must include clinical historyDocumentation must include clinical history
+ 1 more action items

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CPT, HCPCS, and ICD-10 Codes for Dermoscopy and Total Body Photography Under CPB 0188

Covered CPT Codes (When Selection Criteria Are Met)

Code Type Description
96904 CPT Whole body integumentary photography, for monitoring of high-risk patients with dysplastic nevus syndrome

Not Covered / Experimental CPT Codes

Code Type Description Reason
0089U CPT Oncology (melanoma), gene expression profiling by RTqPCR, PRAME and LINC00518, superficial collection Experimental — DermTech PLA; predictive clinical value not established
0258U CPT Autoimmune (psoriasis), mRNA, next-generation sequencing, gene expression profiling of 50–100 genes Experimental — Mind.Px mRNA patch; psoriasis biologic selection value not established
0470T CPT Optical coherence tomography (OCT) for microstructural and morphological imaging of skin, image acquisition Experimental — OCT; clinical value not established
+ 11 more codes

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Key ICD-10-CM Diagnosis Codes

Code Description
C43.0 Malignant melanoma of lip
C43.1 Malignant melanoma of eyelid
C43.2 Malignant melanoma of ear and external auricular canal
+ 15 more codes

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Note: The full policy lists 81 ICD-10-CM codes. Review the complete list at CPB 0188 on Aetna's site to confirm applicable diagnosis codes for your patient mix.


If your practice offers advanced dermatologic imaging — RCM, OCT, gene expression testing — and you have a significant Aetna patient population, talk to your compliance officer before the December 18, 2025 effective date. The experimental list in CPB 0188 is broad. Some of these exclusions will surprise practices that have been billing these codes without denial. Better to audit now than to unwind six months of denied claims in Q1 2026.


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